Syntheses of novel chiral 2,5-dialkyl-7-azabicyclo[2.2.1]heptanes and 2,5-dialkyl-7-thiobicyclo[2.2.1]heptanes

被引：7

作者：

Xiao, DM ^{[1
]}

Zhang, ZG ^{[1
]}

Jiang, QZ ^{[1
]}

Zhang, XM ^{[1
]}

机构：

[1] Penn State Univ, Dept Chem, University Pk, PA 16802 USA

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 30期

基金：

美国国家科学基金会;

关键词：

D O I：

10.1016/S0040-4039(98)00989-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

New C-2-symmetric chiral amines with a rigid bicyclic framework have been synthesized via hydrogenation of monoazides catalyzed by 5% Pd/C in methanol. Enantiomerically pure 2,5-dialkyl-7-thiobicyclo[2.2.1]heptanes were made from readily available materials. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：5331 / 5334

页数：4

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