Kaposi's sarcoma herpes virus taps into a host microRNA regulatory network

被引：40

作者：

McClure, Lydia V. ^{[1
]}

Sullivan, Christopher S. ^{[1
]}

机构：

[1] Univ Texas Austin, Austin, TX 78712 USA

来源：

CELL HOST & MICROBE | 2008年 / 3卷 / 01期

关键词：

D O I：

10.1016/j.chom.2007.12.002

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Kaposi's sarcoma-associated herpes virus (KSHV), the causative agent of several neoplasms, has recently been shown to encode 12 microRNAs. mir-155 is a host-encoded microRNA associated with lymphomagenesis. Two new papers provide strong evidence that a KSHV-encoded microRNA and mir-155 share a common set of mRNA targets and binding sites, implying a possible link between viral- and non-viral-mediated tumorigenesis.

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页码：1 / 3

页数：3

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