Correlation dimension analysis of heart rate variability in patients with dilated cardiomyopathy

A correlation dimension analysis of heart rate variability (HRV) was applied to a group of 55 patients with dilated cardiomyopathy (DCM) and 55 healthy subjects as controls. The 24-h RR time series for each subject was divided into segments of 10,000 beats to determine the correlation dimension (CD) per segment. A study of the influence of the time delay (tag) in the calculation of CD was performed. Good discrimination between both groups (p < 0.005) was obtained with tag values of 5 or greater. CD values of DCM patients (8.4 +/- 1.9) were significantly lower than CD values for controls (9.5 +/- 1.9). An analysis of CD values of HRV showed that for healthy people, CD night values (10.6 +/- 1.8) were significant greater than CD day values (9.2 +/- 1.9), revealing a circadian rhythm. In DCM patients, this circadian rhythm was lost and there were no differences between CD values in day (8.8 +/- 2.4) and night (8.9 +/- 2. 1). (c) 2005 Elsevier Ireland Ltd. All rights reserved.