Blast-induced Mild Traumatic Brain Injury

被引:136
作者
Elder, Gregory A. [1 ,2 ,3 ]
Mitsis, Effie M. [2 ,4 ]
Ahlers, Stephen T. [5 ]
Cristian, Adrian [4 ,6 ]
机构
[1] James J Peters Dept Vet Affairs Med Ctr, Neurol Serv, Bronx, NY 10468 USA
[2] Mt Sinai Sch Med, Dept Psychiat, New York, NY 10029 USA
[3] Mt Sinai Sch Med, Dept Neurol, New York, NY 10029 USA
[4] James J Peters Vet Affairs Med Ctr, Rehabil Med Serv, Bronx, NY 10468 USA
[5] Naval Med Res Ctr, Operat & Undersea Med Directorate, Silver Spring, MD 20910 USA
[6] Mt Sinai Sch Med, Dept Rehabil Med, New York, NY 10029 USA
关键词
Blast-related brain injury; Improvised explosive device; Posttraumatic stress disorder; Traumatic brain injury; POSTTRAUMATIC-STRESS-DISORDER; CENTRAL-NERVOUS-SYSTEM; DIFFUSE AXONAL INJURY; ADULT-RAT BRAIN; PERSISTENT POSTCONCUSSIVE SYMPTOMS; TYMPANIC-MEMBRANE PERFORATION; LASTING IMPULSE NOISE; NON-PENETRATIVE BLAST; WHITE-MATTER INJURY; HEAD-INJURY;
D O I
10.1016/j.psc.2010.08.001
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
Traumatic brain injury (TBI) has been a major cause of mortality and morbidity in the wars in Iraq and Afghanistan Blast exposure has been the most common cause of TBI, occurring through multiple mechanisms What is less clear is whether the primary blast wave causes brain damage through mechanisms that are distinct from those common in civilian TBI and whether multiple exposures to low-level blast can lead to long-term sequelae Complicating TBI in soldiers is the high prevalence of posttraumatic stress disorder At present the relationship is unclear Resolution of these issues will affect both treatment strategies and strategies for the protection of troops in the field
引用
收藏
页码:757 / +
页数:26
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