Two-year follow-up of a prospective randomised trial of electrovaporization versus resection of prostate

被引:26
作者
Hammadeh, MY [1 ]
Madaan, S [1 ]
Singh, M [1 ]
Philp, T [1 ]
机构
[1] Whipps Cross Hosp & Chest Clin, Dept Urol, London E11 1NR, England
关键词
TURP; electrovaporization; outcome; complication;
D O I
10.1159/000019710
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Objectives: Transurethral electrovaporization of the prostate (TUVP) has become a popular, minimally invasive procedure to treat BPH with promising initial results. This study was conducted to compare the efficacy, safety and durability of TUVP with standard TURF. We report the 2-year follow-up. Methods: 104 consecutive men with BPH admitted for surgery were randomised to TUVP (52 patients, mean age: 67.5 years) or TURF (52 patients, mean age: 70.2 years). 47 patients in each arm completed 2-year follow-up. Results: Follow-up data at 2 years show a comparable, significant and maintained improvement in mean IPSS (TUVP: 4.3 vs. TURF: 6.3), quality of life score (TUVP: 1.1 vs. TURF: 1.7), and maximum flow rate (TUVP: 22.4 vs. TURF: 21.2 ml/s) with fall in mean post-void residual volume (TUVP: 18.8 vs. TURF: 22.8 mi). Postoperative impotence reported in TUVP: 17% vs. TURF: 11%(p = 0.49) and retrograde ejaculation TUVP: 72% vs. TURF: 89% (p = 0.47). Two patients in each arm (4%) had urethral stricture and 2 patients (4%) in the resected group had bladder neck stricture. Four patients in each group required re-operation for residual adenoma during the 2 years (4% in each arm each year). Conclusions: Our 2 years' follow-up results suggest that TUVP is as effective as standard TURF in the treatment of moderate-sized BPH with comparable durability.
引用
收藏
页码:188 / 192
页数:5
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