[3H]LY341495, a highly potent, selective and novel radioligand for labeling group II metabotropic glutamate receptors

被引：40

作者：

Ornstein, PL ^{[1
]}

Arnold, MB ^{[1
]}

Bleisch, TJ ^{[1
]}

Wright, RA ^{[1
]}

Wheeler, WJ ^{[1
]}

Schoepp, DD ^{[1
]}

机构：

[1] Eli Lilly & Co, Lilly Res Labs, Lilly Corp Ctr, Indianapolis, IN 46285 USA

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1998年 / 8卷 / 14期

关键词：

D O I：

10.1016/S0960-894X(98)00329-1

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

We report herein the synthesis and pharmacological characterization of a tritiated version of the potent and selective cyclopropyl amino acid LY341495 as a radioligand to label group II metabotropic glutamate receptors in rat brain homogenates. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：1919 / 1922

页数：4

共 11 条

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