Fat embolism

被引:205
作者
Mellor, A [1 ]
Soni, N [1 ]
机构
[1] Chelsea & Westminster Hosp, London SW10 9NH, England
关键词
fat embolism; incidence; aetiology; pathophysiology; diagnosis; treatment;
D O I
10.1046/j.1365-2044.2001.01724.x
中图分类号
R614 [麻醉学];
学科分类号
100217 ;
摘要
Fat embolism syndrome is a collection of respiratory, haematological, neurological and cutaneous symptoms and signs associated with trauma and other disparate surgical and medical conditions. The incidence of the clinical syndrome is low (< 1% in retrospective reviews) whilst the embolisation of marrow fat appears to be an almost inevitable consequence of long bone fractures. There is debate over the pathogenesis of fat embolism syndrome and it seems a variety of factors interact to produce a spectrum of end organ damage. Many therapeutic interventions and prophylactic strategies have been tried with varying success. Current treatments are supportive and the condition is usually associated with a good outcome. The literature on fat embolism syndrome is extensive and this review aims to discuss the incidence, aetiology, pathophysiology, diagnosis and treatment of fat embolism.
引用
收藏
页码:145 / 154
页数:10
相关论文
共 101 条
[1]  
Arroyo J S, 1994, J Arthroplasty, V9, P449, DOI 10.1016/0883-5403(94)90057-4
[2]  
ARTHURS MH, 1993, W INDIAN MED J, V42, P115
[3]  
Ballas SK, 1998, ANN CLIN LAB SCI, V28, P144
[4]  
Barre J, 1997, REV CHIR ORTHOP, V83, P9
[5]  
BASELGA J, 1991, BONE MARROW TRANSPL, V7, P485
[6]  
Behn C, 1997, Versicherungsmedizin, V49, P89
[7]   IMPROVED OUTCOME WITH FEMUR FRACTURES - EARLY VS DELAYED FIXATION [J].
BEHRMAN, SW ;
FABIAN, TC ;
KUDSK, KA ;
TAYLOR, JC .
JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE, 1990, 30 (07) :792-798
[8]  
BOEZAART AP, 1990, S AFR MED J, V78, P693
[9]   EARLY VERSUS DELAYED STABILIZATION OF FEMORAL FRACTURES - A PROSPECTIVE RANDOMIZED STUDY [J].
BONE, LB ;
JOHNSON, KD ;
WEIGELT, J ;
SCHEINBERG, R .
JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME, 1989, 71A (03) :336-340
[10]  
Bulger EM, 1997, ARCH SURG-CHICAGO, V132, P435