Resolution of hepatitis B viremia in a renal transplant recipient treated with alpha-2b interferon

被引：7

作者：

Post, AB

Hricik, DE

Sterling, RK

Bartucci, MR

Jacobs, GH

Schulak, JA

机构：

[1] Case Western Reserve Univ, Sch Med, Dept Med, Cleveland, OH 44106 USA

[2] Case Western Reserve Univ, Sch Med, Dept Surg, Cleveland, OH 44106 USA

[3] Case Western Reserve Univ, Sch Med, Inst Pathol, Cleveland, OH 44106 USA

[4] Univ Hosp Cleveland, Transplantat Serv, Cleveland, OH 44106 USA

来源：

NEPHRON | 1998年 / 79卷 / 04期

关键词：

hepatitis B; interferon; kidney transplant;

D O I：

10.1159/000045094

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

A renal transplant patient developed symptomatic hepatitis after withdrawal from corticosteroids. Tests for hepatitis B e antigen and hepatitis B viral DNA were both positive prior to treatment with 1 million units alpha interferon three times weekly for 3 weeks followed by an increase to 3 million units alpha interferon three times weekly for a total of 16 weeks, At the end of treatment, hepatitis had clinically resolved with conversion to a hepatitis B e antibody positive and hepatitis B e antigen and viral DNA negative state. The renal allograft function remained excellent throughout the course of therapy with interferon.

引用

收藏

页码：469 / 471

页数：3

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