West Nile virus investigations in South Moravia, Czechland

被引:47
作者
Hubálek, Z
Savage, HM
Halouzka, J
Juricová, Z
Sanogo, YO
Lusk, S
机构
[1] Acad Sci Czech Republ, Inst Vertebrate Biol, Dept Med Zool, CZ-69142 Valtice, Czech Republic
[2] Acad Sci Czech Republ, Inst Vertebrate Biol, Dept Aquat Ecosyst, CZ-69142 Valtice, Czech Republic
[3] Ctr Dis Control & Prevent, Div Vector Borne Infect Dis, Ft Collins, CO USA
关键词
D O I
10.1089/vim.2000.13.427
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Seven virus isolates were obtained from 11,334 mosquitoes after the 1997 Morava River flooding in South Moravia (Czech Republic): 6 strains of Tahyna bunyavirus, California antigenic group (5 from Aedes vexans, 1 from Ae. cinereus), and 1 strain of West Nile flavivirus (WNV) from Culex pipiens. In 1999, one isolate of Tahyna virus from Ae. vexans and one isolate of WNV from Cx. pipiens were recovered from a total of 14,354 mosquitoes examined in the same area, whereas no virus was detected there in 1,179 overwintering mosquitoes (mostly Cx. pipiens) in March 2000. The infection rate of mosquitoes with arboviruses was significantly higher in 1997, the year of the flood and an enormously high population density of mosquitoes. Antibodies neutralizing WNV were detected in 13 of 619 (2.1%) hospitalized patients or persons seeking outpatient clinics of the area in 1997. Five of the seroreactors revealed clinical symptoms compatible with West Nile fever: in 2 of them (children), recent infection with WNV was confirmed by a significant increase of antibody titer between acute and convalescent serum samples.
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页码:427 / 433
页数:7
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