How does TAP pump peptides? Insights from DNA repair and traffic ATPases

被引：20

作者：

Reits, EAJ ^{[1
]}

Griekspoor, AC ^{[1
]}

Neefjes, J ^{[1
]}

机构：

[1] Netherlands Canc Inst, Dept Tumor Biol, NL-1066 CX Amsterdam, Netherlands

来源：

IMMUNOLOGY TODAY | 2000年 / 21卷 / 12期

关键词：

D O I：

10.1016/S0167-5699(00)01720-5

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

This article presents an integral model of TAP function that visualizes how peptide and ATP drive the conformational changes required for pore opening and peptide transfer into the major histocompatibility complex (MHC) class I loading complex.

引用

页码：598 / 600

页数：3

共 23 条

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