Sequencing the Oxytricha trifallax macronuclear genome:: a pilot project

被引：31

作者：

Doak, TG

Cavalcanti, ARO

Stover, NA

Dunn, DM

Weiss, R

Herrick, G

Landweber, LF ^{[1
]}

机构：

[1] Univ Utah, Salt Lake City, UT 84132 USA

[2] Princeton Univ, Princeton, NJ 08544 USA

[3] Univ Utah, Utah Genome Depot, Salt Lake City, UT 84132 USA

来源：

TRENDS IN GENETICS | 2003年 / 19卷 / 11期

关键词：

D O I：

10.1016/j.tig.2003.09.013

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Ciliates, microbial eukaryotes, have been important experimental organisms for >100 years, contributing to the discovery and understanding of self-splicing RNA, telomere biochemistry and transcriptional regulation by histone modification. We have completed a pilot sequencing project of the Oxytricha trifallax macronuclear (MAC) genome. When complete, this genome sequence, along with the emerging Tetrahymena thermophila and Paramecium tetraurelia sequences, will provide an important resource for basic eukaryotic cell biology, molecular evolution and the related apicomplexan parasites, such as Plasmodium spp.

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页码：603 / 607

页数：5

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