Effectiveness of bupropion for smoking cessation during pregnancy

被引：51

作者：

Chan, B ^{[1
]}

Einarson, A ^{[1
]}

Koren, G ^{[1
]}

机构：

[1] Hosp Sick Children, Div Clin Pharmacol, Motherisk Program, Toronto, ON M5G 1X8, Canada

来源：

JOURNAL OF ADDICTIVE DISEASES | 2005年 / 24卷 / 02期

关键词：

bupropion; pregnancy; smokers; nicotine;

D O I：

10.1300/J069v24n02_02

中图分类号：

R194 [卫生标准、卫生检查、医药管理];

学科分类号：

摘要：

Gestational smoking has been established as a risk to the fetus. However, many pregnant smokers are unable to quit due to the highly addictive nature of nicotine. Nicotine replacement therapy has failed in several studies in pregnant women. In a prospective matched, controlled observational study, of 22 pregnant smokers receiving bupropion, 10 (45%) ceased smoking, as compared to 3 (14%) of 22 controls (p = 0.047). Bupropion appears to be effective for smoking cessation therapy during pregnancy.

引用

页码：19 / 23

页数：5