Controversies and ethical issues in cancer-genetics clinics

被引：45

作者：

Harris, M ^{[1
]}

Winship, I ^{[1
]}

Spriggs, M ^{[1
]}

机构：

[1] Royal Childrens Hosp, Genet Hlth Serv Victoria, Murdoch Childrens Res Inst, Parkville, Vic 3050, Australia

来源：

LANCET ONCOLOGY | 2005年 / 6卷 / 05期

基金：

英国医学研究理事会;

关键词：

D O I：

10.1016/S1470-2045(05)70166-2

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Genetic testing is a powerful technology that enables prediction of future health status. Testing for cancer-predisposition genes provides information for both the individual and his or her family. The use of this information reaches beyond the medical sphere to the psychological, social, legal, and ethical. The important issues include informed consent, autonomy, confidentiality, justice, disclosure and non-disclosure, duty to warn, genetic discrimination, predictive genetic testing of children, preimplantation genetic diagnosis, and patenting of cancer-predisposition genes.

引用

页码：301 / 310

页数：10

共 65 条

[1]

*AM SOC HUM GEN SO, 1998, J HUM GENET, V62, P474

[2]

[Anonymous], 1999, Fertil Steril, V72, P595

[3]

[Anonymous], ETH PAT DNA

[4] Life insurance and breast cancer risk assessment: Adverse selection, genetic testing decisions, and discrimination [J].

Armstrong, K ;

Weber, B ;

FitzGerald, G ;

Hershey, JC ;

Pauly, MV ;

Lemaire, J ;

Subramanian, K ;

Asch, DA .

AMERICAN JOURNAL OF MEDICAL GENETICS PART A, 2003, 120A (03) :359-364

[5]

*AUSTR LAW REF COM, 2004, 68 AUSTR LAW REF COM

[6]

Australian Government Department of Health, NAT HOSP COST DAT CO

[7]

Australian Law Reform Commission, 2003, 96 AUSTR LAW REF COM

[8] Genetic counseling program in familial breast cancer:: Analysis of its effectiveness, cost and cost-effectiveness ratio [J].

Balmaña, J ;

Sanz, J ;

Bonfill, X ;

Casado, A ;

Rué, M ;

Gich, I ;

Díez, O ;

Sabaté, JM ;

Baiget, M ;

Alonso, MC .

INTERNATIONAL JOURNAL OF CANCER, 2004, 112 (04) :647-652

[9]

Beauchamp T.L., 2001, PRINCIPLES BIOMEDICA, V5th, P57

[10]

Chikhaoui Y, 2002, INT J TECHNOL ASSESS, V18, P67

← 1 2 3 4 5 6 7 →