Assessing the global threat from Zika virus

被引：285

作者：

Lessler, Justin ^{[1
]}

Chaisson, Lelia H. ^{[1
]}

Kucirka, Lauren M. ^{[1
,2
]}

Bi, Qifang ^{[1
]}

Grantz, Kyra ^{[3
]}

Salje, Henrik ^{[1
,4
]}

Carcelen, Andrea C. ^{[5
]}

Ott, Cassandra T. ^{[1
]}

Sheffield, Jeanne S. ^{[6
]}

Ferguson, Neil M. ^{[7
]}

Cummings, Derek A. T. ^{[3
]}

Metcalf, C. Jessica E. ^{[8
,9
]}

Rodriguez-Barraquer, Isabel ^{[1
]}

机构：

[1] Johns Hopkins Bloomberg Sch Publ Hlth, Dept Epidemiol, Baltimore, MD 21205 USA

[2] Johns Hopkins Univ, Sch Med, Dept Surg, Baltimore, MD 21205 USA

[3] Univ Florida, Emerging Pathogens Inst, Dept Biol, Gainesville, FL USA

[4] Inst Pasteur, Math Modelling Infect Dis Unit, Paris, France

[5] Johns Hopkins Bloomberg Sch Publ Hlth, Dept Int Hlth, Baltimore, MD USA

[6] Johns Hopkins Univ, Sch Med, Dept Obstet & Gynecol, Baltimore, MD 21205 USA

[7] Imperial Coll London, Sch Publ Hlth, Dept Med, London, England

[8] Princeton Univ, Dept Ecol & Evolutionary Biol, Princeton, NJ 08544 USA

[9] Princeton Univ, Off Populat Res, Princeton, NJ 08544 USA

来源：

SCIENCE | 2016年 / 353卷 / 6300期

关键词：

YELLOW-FEVER; ARBOVIRUS INFECTIONS; SEXUAL TRANSMISSION; FRENCH-POLYNESIA; AEDES-AEGYPTI; DENGUE VIRUS; WEST-NILE; JAPANESE ENCEPHALITIS; VECTOR CONTROL; BORNE VIRUSES;

D O I：

10.1126/science.aaf8160

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

First discovered in 1947, Zika virus (ZIKV) infection remained a little-known tropical disease until 2015, when its apparent association with a considerable increase in the incidence of microcephaly in Brazil raised alarms worldwide. There is limited information on the key factors that determine the extent of the global threat from ZIKV infection and resulting complications. Here, we review what is known about the epidemiology, natural history, and public health effects of ZIKV infection, the empirical basis for this knowledge, and the critical knowledge gaps that need to be filled.

引用

页数：10

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