Serology: a robust indicator of malaria transmission intensity?

被引:216
作者
Corran, Patrick [1 ]
Coleman, Paul [1 ,2 ]
Riley, Eleanor [1 ]
Drakeley, Chris [1 ,3 ]
机构
[1] London Sch Hyg & Trop Med, Dept Infect & Trop Dis, London WC1E 7HT, England
[2] Natl Inst Biol Stand & Controls, Biotherapeut Div, Potters Bar EN6 3QG, Herts, England
[3] Kilimanjaro Christian Med Ctr, Joint Malaria Program, Moshi, Tanzania
基金
英国惠康基金;
关键词
D O I
10.1016/j.pt.2007.08.023
中图分类号
R38 [医学寄生虫学]; Q [生物科学];
学科分类号
07 ; 0710 ; 09 ; 100103 ;
摘要
To estimate the burden of malarial disease, and evaluate the likely effects of control strategies, requires reliable predictions of malaria transmission intensity. It has long been suggested that antimalarial antibody prevalences could provide a more accurate estimate of transmission intensity than traditional measures such as parasite prevalence or entomological inoculation rates, but there has been no systematic evaluation of this approach. Now, the availability of well characterized malarial antigens allows us to test whether serological measurements provide a practical method for estimating transmission. Here we present a suggested methodology, highlight the advantages and shortcomings of serological measurements of malaria transmission and identify areas in which further work is desirable.
引用
收藏
页码:575 / 582
页数:8
相关论文
共 57 条
[1]   Malaria epidemic early warning and detection in African highlands [J].
Abeku, TA ;
Hay, SI ;
Ochola, S ;
Langi, P ;
Beard, B ;
de Vlas, SJ ;
Cox, J .
TRENDS IN PARASITOLOGY, 2004, 20 (09) :400-405
[2]  
BEKESSY A, 1976, B WORLD HEALTH ORGAN, V54, P685
[3]   Relationship between altitude and intensity of malaria transmission in the Usambara Mountains, Tanzania [J].
Bodker, R ;
Akida, J ;
Shayo, D ;
Kisinza, W ;
Msangeni, HA ;
Pedersen, EM ;
Lindsay, SW .
JOURNAL OF MEDICAL ENTOMOLOGY, 2003, 40 (05) :706-717
[4]   Distinct interethnic differences in immunoglobulin G class/subclass and immunoglobulin M antibody responses to malaria antigens but not in immunoglobulin G responses to nonmalarial antigens in sympatric tribes living in West Africa [J].
Bolad, A ;
Farouk, SE ;
Israelsson, E ;
Dolo, A ;
Doumbo, OK ;
Nebié, I ;
Maiga, B ;
Kouriba, B ;
Luoni, G ;
Sirima, BS ;
Modiano, D ;
Berzins, K ;
Troye-Blomberg, M .
SCANDINAVIAN JOURNAL OF IMMUNOLOGY, 2005, 61 (04) :380-386
[5]  
Chandramohan D, 2001, B WORLD HEALTH ORGAN, V79, P375
[6]   STUDIES ON PERSISTENCE OF MALARIAL ANTIBODY RESPONSE [J].
COLLINS, WE ;
SKINNER, JC ;
JEFFERY, GM .
AMERICAN JOURNAL OF EPIDEMIOLOGY, 1968, 87 (03) :592-+
[7]   Geographical structure of diversity and differences between symptomatic and asymptomatic infections for Plasmodium falciparum vaccine candidate AMA1 [J].
Cortes, A ;
Mellombo, M ;
Mueller, I ;
Benet, A ;
Reeder, JC ;
Anders, RF .
INFECTION AND IMMUNITY, 2003, 71 (03) :1416-1426
[8]   A climate-based distribution model of malaria transmission in sub-Saharan Africa [J].
Craig, MH ;
Snow, RW ;
le Sueur, D .
PARASITOLOGY TODAY, 1999, 15 (03) :105-111
[9]   MALARIA SEROEPIDEMIOLOGY - COMPARISON BETWEEN INDIRECT FLUORESCENT-ANTIBODY TEST AND ENZYME-IMMUNOASSAY USING BLOODSPOT ELUATES [J].
DECARVALHO, ME ;
FERREIRA, MU ;
DESOUZA, MRD ;
NINOMIA, RT ;
MATOS, GF ;
CAMARGO, LMA ;
FERREIRA, CS .
MEMORIAS DO INSTITUTO OSWALDO CRUZ, 1992, 87 (02) :205-208
[10]   IS IMMUNITY TO MALARIA REALLY SHORT-LIVED [J].
DELORON, P ;
CHOUGNET, C .
PARASITOLOGY TODAY, 1992, 8 (11) :375-378