Circadian regulation of gene expression in animals

被引：97

作者：

Ripperger, JA ^{[1
]}

Schibler, U ^{[1
]}

机构：

[1] Univ Geneva, Dept Biol Mol, CH-1211 Geneva 4, Switzerland

来源：

CURRENT OPINION IN CELL BIOLOGY | 2001年 / 13卷 / 03期

关键词：

D O I：

10.1016/S0955-0674(00)00220-9

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Circadian timekeepers reside in most body cells of Drosophila and mammals. The discovery of new clock genes suggests that circadian oscillations are generated by interconnected feedback loops employing transcriptional and post-translational mechanisms. In mammals, a master pacemaker localized in the suprachiasmatic nucleus synchronizes peripheral clocks via humoral cues. However, restricted feeding can uncouple peripheral oscillators from the suprachiasmatic pacemaker.

引用

页码：357 / 362

页数：6

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