Circulating tumor cell enumeration by the CellSearch system: The clinician's guide to breast cancer treatment?

被引：77

作者：

Beije, Nick ^{[1
]}

Jager, Agnes ^{[1
]}

Sleijfer, Stefan ^{[1
]}

机构：

[1] Inst Canc Res, Erasmus Med Ctr, Dept Med Oncol & Canc Genom Netherlands, Rotterdam, Netherlands

来源：

CANCER TREATMENT REVIEWS | 2015年 / 41卷 / 02期

关键词：

Circulating tumor cells; CTC; Breast cancer; Clinical decision-making; Recommendations; ADJUVANT CHEMOTHERAPY; GENE-EXPRESSION; SOLID TUMORS; SURVIVAL; TRASTUZUMAB; RECOMMENDATIONS; PROGRESSION; PREDICTION; WOMEN;

D O I：

10.1016/j.ctrv.2014.12.008

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 [肿瘤学];

摘要：

Circulating tumor cells (CTCs) are cancer cells that are present in the blood of patients with solid cancers and are shed from existing tumor lesions into the blood stream. The enumeration of CTCs has long been considered to hold great promise in guiding treatment decision-making in breast cancer patients. However, guidelines on how to use CTC enumeration in clinical decision-making in primary breast cancer and metastatic breast cancer are lacking. Here, we set out to review the most relevant literature to date, to ultimately come to general recommendations regarding the use of CTC enumeration in primary breast cancer and metastatic breast cancer. (C) 2014 Elsevier Ltd. All rights reserved.

引用

页码：144 / 150

页数：7

共 45 条

[1]

Abe O, 2005, LANCET, V366, P2087, DOI 10.1016/s0140-6736(05)66544-0

[2]

Tumor cells circulate in the peripheral blood of all major carcinomas but not in healthy subjects or patients with nonmalignant diseases [J].

Allard, WJ ;

Matera, J ;

Miller, MC ;

Repollet, M ;

Connelly, MC ;

Rao, C ;

Tibbe, AGJ ;

Uhr, JW ;

Terstappen, LWMM .

CLINICAL CANCER RESEARCH, 2004, 10 (20) :6897-6904

[3]

[Anonymous], CA CANC J CLIN, DOI DOI 10.3322/CAAC.20107

[4]

Gene expression profiling in breast cancer: A clinical perspective [J].

Arpino, Grazia ;

Generali, Daniele ;

Sapino, Anna ;

Lucia, Del Matro ;

Frassoldati, Antonio ;

de Laurentis, Michelino ;

Paolo, Pronzato ;

Mustacchi, Giorgio ;

Cazzaniga, Marina ;

De Placido, Sabino ;

Conte, Pierfranco ;

Cappelletti, Mariarosa ;

Zanoni, Vanessa ;

Antonelli, Andrea ;

Martinotti, Mario ;

Puglisi, Fabio ;

Berruti, Alfredo ;

Bottini, Alberto ;

Dogliotti, Luigi .

BREAST, 2013, 22 (02) :109-120

[5]

Plasticity of disseminating cancer cells in patients with epithelial malignancies [J].

Bednarz-Knoll, Natalia ;

Alix-Panabieres, Catherine ;

Pantel, Klaus .

CANCER AND METASTASIS REVIEWS, 2012, 31 (3-4) :673-687

[6]

Bidard FC, 2012, CANC RES, P72

[7]

Clinical validity of circulating tumour cells in patients with metastatic breast cancer: a pooled analysis of individual patient data [J].

Bidard, Francois-Clement ;

Peeters, Dieter J. ;

Fehm, Tanja ;

Nole, Franco ;

Gisbert-Criado, Rafael ;

Mavroudis, Dimitrios ;

Grisanti, Salvatore ;

Generali, Daniele ;

Garcia-Saenz, Jose A. ;

Stebbing, Justin ;

Caldas, Carlos ;

Gazzaniga, Paola ;

Manso, Luis ;

Zamarchi, Rita ;

Fernandez de Lascoiti, Angela ;

De Mattos-Arruda, Leticia ;

Ignatiadis, Michail ;

Lebofsky, Ronald ;

van Laere, Steven J. ;

Meier-Stiegen, Franziska ;

Sandri, Maria-Teresa ;

Vidal-Martinez, Jose ;

Politaki, Eleni ;

Consoli, Francesca ;

Bottini, Alberto ;

Diaz-Rubio, Eduardo ;

Krell, Jonathan ;

Dawson, Sarah-Jane ;

Raimondi, Cristina ;

Rutten, Annemie ;

Janni, Wolfgang ;

Munzone, Elisabetta ;

Caranana, Vicente ;

Agelaki, Sofi A. ;

Almici, Camillo ;

Dirix, Luc ;

Solomayer, Erich-Franz ;

Zorzino, Laura ;

Johannes, Helene ;

Reis-Filho, Jorge S. ;

Pantel, Klaus ;

Pierga, Jean-Yves ;

Michiels, Stefan .

LANCET ONCOLOGY, 2014, 15 (04) :406-414

[8]

Time-Dependent Prognostic Impact of Circulating Tumor Cells Detection in Non-Metastatic Breast Cancer: 70-Month Analysis of the REMAGUS02 Study [J].

Bidard, Francois-Clement ;

Belin, Lisa ;

Delaloge, Suzette ;

Lerebours, Florence ;

Ngo, Charlotte ;

Reyal, Fabien ;

Alran, Severine ;

Giacchetti, Sylvie ;

Marty, Michel ;

Lebofsky, Ronald ;

Pierga, Jean-Yves .

INTERNATIONAL JOURNAL OF BREAST CANCER, 2013, 2013

[9]

Clinical application of circulating tumor cells in breast cancer: overview of the current interventional trials [J].

Bidard, Francois-Clement ;

Fehm, Tanja ;

Ignatiadis, Michail ;

Smerage, Jeffrey B. ;

Alix-Panabieres, Catherine ;

Janni, Wolfgang ;

Messina, Carlo ;

Paoletti, Costanza ;

Mueller, Volkmar ;

Hayes, Daniel F. ;

Piccart, Martine ;

Pierga, Jean-Yves .

CANCER AND METASTASIS REVIEWS, 2013, 32 (1-2) :179-188

[10]

Circulating Tumor Cells in Patients Undergoing Surgery for Primary Breast Cancer: Preliminary Results of a Pilot Study [J].

Biggers, Brian ;

Knox, Sally ;

Grant, Michael ;

Kuhn, John ;

Nemunatitis, John ;

Fisher, Tammy ;

Lamont, Jeff .

ANNALS OF SURGICAL ONCOLOGY, 2009, 16 (04) :969-971

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