Biosynthesis of PP-V, a monascorubramine homologue, by Penicillium sp AZ

被引：45

作者：

Ogihara, J ^{[1
]}

Kato, J

Oishi, K

Fujimoto, Y

机构：

[1] Nihon Univ, Coll Bioresource Sci, Dept Agr Biol Chem, Kanagawa 2528510, Japan

[2] Tokyo Inst Technol, Dept Chem & Mat Sci, Meguro Ku, Tokyo 1528551, Japan

来源：

JOURNAL OF BIOSCIENCE AND BIOENGINEERING | 2000年 / 90卷 / 06期

关键词：

Monascus; Penicillium; pigment; azaphilone; C-13-acetate;

D O I：

10.1263/jbb.90.678

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 [微生物学]; 0836 [生物工程]; 090102 [作物遗传育种]; 100705 [微生物与生化药学];

摘要：

The biosynthetic pathway of PP-V, a new monascorubramine homologue, was elucidated by C-13-labeling studies. The [1-C-13] Of acetate was incorporated into 2-, 3a-, 4a-, 6-, 8-, 9-, 11-, 13-, 15-, 17-, and 19-Cs of PP-V, and the [2-C-13], into 3-, 4-, 5-, 8a-, 9a-, 10-, 12-, 14-, 16-, 18-, and 20-Cs. These incorporation patterns coincide with those reported in the biosynthesis of a Monascus azaphilone pigment, monascorubrin.

引用

页码：678 / 680

页数：3

共 19 条

[1]

ISOCHROMOPHILONES-III-VI, INHIBITORS OF ACYL-COA - CHOLESTEROL ACYLTRANSFERASE PRODUCED BY PENICILLIUM-MULTICOLOR-FO-3216 [J].