Reducing Consumption of Sugar-Sweetened Beverages Is Associated With Reduced Blood Pressure A Prospective Study Among United States Adults

被引:188
作者
Chen, Liwei [1 ]
Caballero, Benjamin [2 ]
Mitchell, Diane C. [3 ]
Loria, Catherine [4 ]
Lin, Pao-Hwa [5 ]
Champagne, Catherine M. [6 ]
Elmer, Patricia J. [7 ]
Ard, Jamy D. [8 ]
Batch, Bryan C. [9 ]
Anderson, Cheryl A. M. [2 ,10 ]
Appel, Lawrence J. [10 ]
机构
[1] Louisiana State Univ, Hlth Sci Ctr, Sch Publ Hlth, Program Epidemiol, New Orleans, LA 70112 USA
[2] Johns Hopkins Bloomberg Sch Publ Hlth, Ctr Human Nutr, Baltimore, MD USA
[3] Penn State Univ, Dept Nutr Sci, Diet Assessment Ctr, University Pk, PA 16802 USA
[4] NHLBI, Div Prevent & Populat Sci, Bethesda, MD 20892 USA
[5] Duke Univ, Med Ctr, Dept Med, Durham, NC 27710 USA
[6] Pennington Biomed Res Ctr, Baton Rouge, LA USA
[7] Kaiser Permanente Ctr Hlth Res, Portland, OR USA
[8] Univ Alabama Birmingham, Div Clin Nutr & Dietet, Birmingham, AL USA
[9] Duke Univ, Duke Hypertens Ctr, Durham, NC USA
[10] Johns Hopkins Med Inst, Welch Ctr Prevent Epidemiol & Clin Res, Baltimore, MD 21205 USA
基金
美国国家卫生研究院;
关键词
blood pressure; diet; follow-up studies; hypertension; LIFE-STYLE MODIFICATION; METABOLIC SYNDROME; CLINICAL-TRIAL; URIC-ACID; HYPERTENSION; FRUCTOSE; WOMEN; RATS; CAFFEINE; OBESITY;
D O I
10.1161/CIRCULATIONAHA.109.911164
中图分类号
R5 [内科学];
学科分类号
100201 [内科学];
摘要
Background-Increased consumption of sugar-sweetened beverages (SSBs) has been associated with an elevated risk of obesity, metabolic syndrome, and type II diabetes mellitus. However, the effects of SSB consumption on blood pressure (BP) are uncertain. The objective of this study was to determine the relationship between changes in SSB consumption and changes in BP among adults. Methods and Results-This was a prospective analysis of 810 adults who participated in the PREMIER Study (an 18-month behavioral intervention trial). BP and dietary intake (by two 24-hour recalls) were measured at baseline and at 6 and 18 months. Mixed-effects models were applied to estimate the changes in BP in responding to changes in SSB consumption. At baseline, mean SSB intake was 0.9 +/- 1.0 servings per day (10.5 +/- 11.9 fl oz/d), and mean systolic BP/diastolic BP was 134.9 +/- 9.6/84.8 +/- 4.2 mm Hg. After potential confounders were controlled for, a reduction in SSB of 1 serving per day was associated with a 1.8-mm Hg (95% confidence interval, 1.2 to 2.4) reduction in systolic BP and 1.1-mm Hg (95% confidence interval, 0.7 to 1.4) reduction in diastolic BP over 18 months. After additional adjustment for weight change over the same period, a reduction in SSB intake was still significantly associated with reductions in systolic and diastolic BPs (P<0.05). Reduced intake of sugars was also significantly associated with reduced BP. No association was found for diet beverage consumption or caffeine intake and BP. These findings suggest that sugars may be the nutrients that contribute to the observed association between SSB and BP. Conclusions-Reduced consumption of SSB and sugars was significantly associated with reduced BP. Reducing SSB and sugar consumption may be an important dietary strategy to lower BP.
引用
收藏
页码:2398 / 2406
页数:9
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