Dynamin II binds to the trans-Golgi network

被引：47

作者：

Maier, O ^{[1
]}

Knoblich, M ^{[1
]}

Westermann, P ^{[1
]}

机构：

[1] MAX DELBRUCK CTR MOLEC MED,DIV CELL BIOL,D-13125 BERLIN,GERMANY

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1996年 / 223卷 / 02期

关键词：

D O I：

10.1006/bbrc.1996.0876

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Two dynamin II - specific antibodies were used to detect dynamin II attached to highly purified Golgi membranes of HepG2 cells. Within the Golgi apparatus dynamin II is predominantly localized to the trans-Golgi network, as shown by immunoelectron microscopy. Increased binding of dynamin II to the trans-Golgi network in the presence of GTP-gamma-S and a reduced binding upon stimulation of secretion by phorbolester indicates that dynamin II may have a function in post-Golgi vesicle transport. (C) 1996 Academic Press, Inc.

引用

页码：229 / 233

页数：5

共 19 条

[1] DETERGENT INFLUENCE ON RAT-LIVER GALACTOSYLTRANSFERASE ACTIVITIES TOWARDS DIFFERENT ACCEPTORS [J].

BRETZ, R ;

STAUBLI, W .

EUROPEAN JOURNAL OF BIOCHEMISTRY, 1977, 77 (01) :181-192

[2] MULTIPLE FORMS OF DYNAMIN ARE ENCODED BY SHIBIRE, A DROSOPHILA GENE INVOLVED IN ENDOCYTOSIS [J].

CHEN, MS ;

OBAR, RA ;

SCHROEDER, CC ;

AUSTIN, TW ;

POODRY, CA ;

WADSWORTH, SC ;

VALLEE, RB .

NATURE, 1991, 351 (6327) :583-586

[3] INDUCTION OF MUTANT DYNAMIN SPECIFICALLY BLOCKS ENDOCYTIC COATED VESICLE FORMATION [J].

DAMKE, H ;

BABA, T ;

WARNOCK, DE ;

SCHMID, SL .

JOURNAL OF CELL BIOLOGY, 1994, 127 (04) :915-934

[4] DISTINCT FUNCTIONS FOR THE 2 IMPORTIN SUBUNITS IN NUCLEAR-PROTEIN IMPORT [J].

GORLICH, D ;

VOGEL, F ;

MILLS, AD ;

HARTMANN, E ;

LASKEY, RA .

NATURE, 1995, 377 (6546) :246-248

[5] ON THE PREPARATION OF CRYOSECTIONS FOR IMMUNOCYTOCHEMISTRY [J].

GRIFFITHS, G ;

MCDOWALL, A ;

BACK, R ;

DUBOCHET, J .

JOURNAL OF ULTRASTRUCTURE RESEARCH, 1984, 89 (01) :65-78

[6] EFFECTS OF MUTANT RAT DYNAMIN ON ENDOCYTOSIS [J].

HERSKOVITS, JS ;

BURGESS, CC ;

OBAR, RA ;

VALLEE, RB .

JOURNAL OF CELL BIOLOGY, 1993, 122 (03) :565-578

[7]

Kargel E, 1996, YEAST, V12, P333

[8] HVEM TOMOGRAPHY OF THE TRANS-GOLGI NETWORK - STRUCTURAL INSIGHTS AND IDENTIFICATION OF A LACE-LIKE VESICLE COAT [J].

LADINSKY, MS ;

KREMER, JR ;

FURCINITTI, PS ;

MCINTOSH, JR ;

HOWELL, KE .

JOURNAL OF CELL BIOLOGY, 1994, 127 (01) :29-38

[9] CLEAVAGE OF STRUCTURAL PROTEINS DURING ASSEMBLY OF HEAD OF BACTERIOPHAGE-T4 [J].

LAEMMLI, UK .

NATURE, 1970, 227 (5259) :680-+

[10] MULTIPLE TRIMERIC G-PROTEINS ON THE TRANS-GOLGI NETWORK EXERT STIMULATORY AND INHIBITORY EFFECTS ON SECRETORY VESICLE FORMATION [J].

LEYTE, A ;

BARR, FA ;

KEHLENBACH, RH ;

HUTTNER, WB .

EMBO JOURNAL, 1992, 11 (13) :4795-4804

← 1 2 →