The use of a bilaminate artificial skin substitute (Integra™) in acute resurfacing of burns:: an early experience

被引:47
作者
Fitton, AR [1 ]
Drew, P [1 ]
Dickson, WA [1 ]
机构
[1] Morriston Hosp, Welsh Reg Ctr Burns & Plast Surg, Swansea SA6 6NL, W Glam, Wales
来源
BRITISH JOURNAL OF PLASTIC SURGERY | 2001年 / 54卷 / 03期
关键词
artificial skin; Integra; complications; case report;
D O I
10.1054/bjps.2000.3525
中图分类号
R61 [外科手术学];
学科分类号
摘要
Integra(TM) artificial skin provides immediate full-thickness reconstruction for cutaneous bums. The clinical outcome appears to be superior in terms of final function and cosmesis. Consequently the use of such a skin substitute is being heralded as the future treatment of choice, particularly for massive burns where autologous donor skin is limited. The three cases reported here describe the senior author's early experience with Integra and highlight some of the difficulties and successes encountered. A high rate of dermal graft loss and slow epidermal engraftment have tempered the original enthusiasm, but with growing experience the final outcome justifies the continued use of Integra in our unit. (C) 2001 The British Association of Plastic Surgeons.
引用
收藏
页码:208 / 212
页数:5
相关论文
共 21 条
[1]   The 1999 Clinical Research Award - Cultured skin substitutes combined with integra artificial skin to replace native skin autograft and allograft for the closure of excised full-thickness burns [J].
Boyce, ST ;
Kagan, RJ ;
Meyer, NA ;
Yakuboff, KP ;
Warden, GD .
JOURNAL OF BURN CARE & REHABILITATION, 1999, 20 (06) :453-461
[2]   SUCCESSFUL USE OF A PHYSIOLOGICALLY ACCEPTABLE ARTIFICIAL SKIN IN THE TREATMENT OF EXTENSIVE BURN INJURY [J].
BURKE, JF ;
YANNAS, IV ;
QUINBY, WC ;
BONDOC, CC ;
JUNG, WK .
ANNALS OF SURGERY, 1981, 194 (04) :413-428
[3]   IMPROVED SURVIVAL AFTER MASSIVE BURNS [J].
DEMLING, RH .
JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE, 1983, 23 (03) :179-184
[4]   EARLY EXCISION AND GRAFTING VS NONOPERATIVE TREATMENT OF BURNS OF INDETERMINANT DEPTH - A RANDOMIZED PROSPECTIVE-STUDY [J].
ENGRAV, LH ;
HEIMBACH, DM ;
REUS, JL ;
HARNAR, TJ ;
MARVIN, JA .
JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE, 1983, 23 (11) :1001-1004
[5]  
GALLICO GG, 1990, CLIN PLAST SURG, V17, P519
[6]  
GALLICO GG, 1985, CLIN PLAST SURG, V12, P149
[7]   EARLY SURGICAL EXCISION VERSUS CONVENTIONAL THERAPY IN PATIENTS WITH 20 TO 40 PERCENT BURNS - A COMPARATIVE-STUDY [J].
GRAY, DT ;
PINE, RW ;
HARNAR, TJ ;
MARVIN, JA ;
ENGRAV, LH ;
HEIMBACH, DM .
AMERICAN JOURNAL OF SURGERY, 1982, 144 (01) :76-80
[8]   ARTIFICIAL DERMIS FOR MAJOR BURNS - A MULTI-CENTER RANDOMIZED CLINICAL-TRIAL [J].
HEIMBACH, D ;
LUTERMAN, A ;
BURKE, J ;
CRAM, A ;
HERNDON, D ;
HUNT, J ;
JORDAN, M ;
MCMANUS, W ;
SOLEM, L ;
WARDEN, G ;
ZAWACKI, B .
ANNALS OF SURGERY, 1988, 208 (03) :313-320
[9]  
JANZEKOVIC Z, 1975, J TRAUMA, V15, P42
[10]   EXCISION OF BURNS [J].
JANZEKOVIC, Z .
BURNS, 1977, 4 (01) :61-66