Application of KIE and thia approaches in the mechanistic study of a plant stearoyl-ACP Δ9 desaturase

被引：26

作者：

Behrouzian, B

Buist, PH

Shanklin, J

机构：

[1] Carleton Univ, Ottawa Carleton Chem Inst, Dept Chem, Ottawa, ON K1S 5B6, Canada

[2] Brookhaven Natl Lab, Dept Biol, Upton, NY 11973 USA

来源：

CHEMICAL COMMUNICATIONS | 2001年 / 05期

关键词：

D O I：

10.1039/b008972i

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The mechanism of the castor stearoyl-ACP Delta (9) desaturase has been investigated; it has been shown that C-H cleavage at carbons 9 and 10 is not sensitive to deuterium substitution and oxo-trapping experiments using thia analogues revealed that sulfoxidation occurs when the substrate bears sulfur at the 9 and 10 positions.

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页码：401 / 402

页数：2

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