Preparation of helical peptide monolayer-coated gold nanoparticles

被引：59

作者：

Higashi, N ^{[1
]}

Kawahara, J ^{[1
]}

Niwa, M ^{[1
]}

机构：

[1] Doshisha Univ, Fac Engn, Dept Mol Sci & Technol, Kyoto 6100321, Japan

来源：

JOURNAL OF COLLOID AND INTERFACE SCIENCE | 2005年 / 288卷 / 01期

关键词：

gold nanoparticle; peptide; alpha-helix; monolayer; gold plasmon;

D O I：

10.1016/j.jcis.2005.02.086

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

We describe herein the preparation of polypeptide (poly(gamma-benzyl-L-glutamate)) monolayer-covered gold nanoparticles (PBLG(n)SS-Au). Two types of PBLG(n)SS having PBLG segment length n = 20 and 50 were synthesized and successfully attached to the gold nanoparticle surface using the Brust-Schiffern method. The mean sizes of PBLG(n)SS-Au particles and their gold cluster cores in CHCl3, which were evaluated by means of dynamic light scattering and TEM, respectively, demonstrated that the gold cluster surfaces were covered with PBLG monolayers, and their conformation was found to be mainly in alpha-helix on the basis of FT-IR spectroscopy. (c) 2005 Elsevier Inc. All rights reserved.

引用

页码：83 / 87

页数：5

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