A new verdict for an old convict

被引：11

作者：

Pfeifer, GP ^{[1
]}

机构：

[1] City Hope Natl Med Ctr, Beckman Res Inst, Dept Biol, Duarte, CA 91010 USA

来源：

NATURE GENETICS | 2001年 / 29卷 / 01期

关键词：

D O I：

10.1038/ng0901-3

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Certain human cancers and carcinogen-induced rodent tumors commonly contain Kras2 mutations. This activated form of ras has always been described as a dominant oncogene. A new study indicates that wildtype Kras2 has properties of a tumor suppressor gene and may have the capacity to reduce the transforming potential of oncogenically activated ras.

引用

页码：3 / 4

页数：2

共 13 条

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