Brain weight in autism:: Normal in the majority of cases, megalencephalic in rare cases

被引：60

作者：

Courchesne, E

Müller, RA

Saitoh, O

机构：

[1] Univ Calif San Diego, Sch Med, Dept Neurosci, La Jolla, CA 92093 USA

[2] Univ Calif San Diego, Dept Cognit Sci, La Jolla, CA 92093 USA

[3] Childrens Hosp, Res Ctr, Lab Res Neurosci Autism, San Diego, CA USA

[4] Natl Ctr Hosp Mental Nervous & Muscular Disorders, Natl Ctr Neurol & Psychiat, Outpatient Dept, Tokyo, Japan

来源：

NEUROLOGY | 1999年 / 52卷 / 05期

关键词：

D O I：

10.1212/WNL.52.5.1057

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The brain weights of 21 postmortem autism cases (5 new and 16 previously published) were compared with normal brain weights from six autopsy studies. Of the 21 cases, 17 had normal brain weights and 1 was micrencephalic. Compared with the normal median (1,460 g), three autism cases were megalencephalic: two (1,810 g and 1,820 g) had been previously reported and one (1,880 g) was a new case. Brain weight is thus normal in most postmortem cases of autism. There are, however, rare cases of megalencephaly and possibly micrencephaly.

引用

页码：1057 / 1059

页数：3

共 10 条

[1] A clinicopathological study of autism [J].