Estrogen receptor β:: Re-evaluation of estrogen and antiestrogen signaling

被引：96

作者：

Giguère, V

Tremblay, A

Tremblay, GB

机构：

[1] Royal Victoria Hosp, Mol Oncol Grp, Montreal, PQ H3A 1A1, Canada

[2] McGill Univ, Dept Biochem, Montreal, PQ, Canada

[3] McGill Univ, Dept Med, Montreal, PQ, Canada

[4] McGill Univ, Dept Oncol, Montreal, PQ, Canada

来源：

STEROIDS | 1998年 / 63卷 / 5-6期

关键词：

nuclear receptors; antiestrogens; receptor coregulator;

D O I：

10.1016/S0039-128X(98)00024-5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 [生物化学与分子生物学]; 081704 [应用化学];

摘要：

Estrogen is of vital importance for the development and control of reproductive functions. Until recently, estrogen was believed to regulate complex programs of gene expression by binding to an unique nuclear receptor belonging to the superfamily of ligand-dependent transcription factors. However, the identification of a second estrogen receptor, referred to as ERP, is leading to a re-evaluation of estrogen signaling and physiology. (C) 1998 by Elsevier Science Inc.

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页码：335 / 339

页数：5

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