Neuroimaging of serotonin transporters in post-stroke pathological crying

被引：40

作者：

Murai, T

Barthel, H

Berrouschot, J

Sorger, D

von Cramon, DY

Müller, U

机构：

[1] Leipzig Univ Hosp, Dept Psychiat, D-04103 Leipzig, Germany

[2] Max Planck Inst Cognit Neurosci, D-04103 Leipzig, Germany

[3] Kyoto Univ Hosp, Dept Neuropsychiat, Kyoto 606, Japan

[4] Leipzig Univ Hosp, Dept Nucl Med, D-04103 Leipzig, Germany

[5] Leipzig Univ Hosp, Dept Neurol, D-04103 Leipzig, Germany

[6] Leipzig Univ Hosp, Dept Cognit Neurol, D-04103 Leipzig, Germany

来源：

PSYCHIATRY RESEARCH-NEUROIMAGING | 2003年 / 123卷 / 03期

关键词：

single photon emission computed tomography; I-123]beta-CIT; serotonin; brainstem; stroke;

D O I：

10.1016/S0925-4927(03)00065-9

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Pathological crying (PC) is a neuropsychiatric disorder characterized by an excessive tendency towards crying after brain damage. To elucidate the role of serotonin neurotransmission for PC, a pilot study was performed using single photon emission computed tomography with [I-123]beta-CIT to estimate central (midbrain/pons and thalamus/hypothalamus) serotonin transporter (SERT) densities in 15 stroke patients who did or did not have PC. SERT binding ratios in midbrain/pons were significantly lower in the PC subgroup. (C) 2003 Elsevier Ireland Ltd. All rights reserved.

引用

页码：207 / 211

页数：5

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