Endovascular treatment of ruptured abdominal aortic aneurysms: A shift of the paradigm?

被引:93
作者
Larzon, T [1 ]
Lindgren, R [1 ]
Norgren, L [1 ]
机构
[1] Orebro Univ Hosp, Dept Surg, SE-70185 Orebro, Sweden
关键词
abdominal aortic aneurysm; rupture; endovascular repair; bifurcated stentgraft; occlusion balloon; local anesthesia; open surgery; mortality; outcome analysis;
D O I
10.1583/04-1469.1
中图分类号
R61 [外科手术学];
学科分类号
摘要
Purpose: To compare endovascular aneurysm repair (EVAR) of ruptured abdominal aortic aneurysms (rAAA) to the results with open surgery. Methods: Between May 2001 and January 2004, 50 patients were diagnosed with rAAA. Fifteen (30%) patients (14 men; median age 73 years, range 58-85) underwent EVAR, while 26 (52%) patients (23 men; median age 75 years, range 60-84) had open surgery. Nine (18%) patients (5 men; median age 86 years, range 77-91) were not operated upon. Circulatory shock was defined as systolic blood pressure < 80 mmHg. Mortality was defined as death within 30 days after operation; in cases where hospital stay exceeded 30 days, in-hospital mortality was registered. Five risk factors (age > 76 years, loss of consciousness, hemoglobin < 90 g/L, creatinine > 190 mu mol/L, and electrocardiographic ischernia) were analyzed. Results: In the EVAR group, 93% (14/15) of the aneurysms were excluded from the bloodstream; there were 2 (13%) conversions: 1 intraoperatively for stent-graft migration and another owing to dissection prior to hospital discharge. Mortality after open surgery was 46% (12/26) versus 13% (2/15) in the EVAR group (p > 0.05). Univariate analysis without considering variables other than mortality resulted in OR 5.4 (95% Cl 0.9 to 58; p=0.07). Considering risk factors and shock, multivariate analysis resulted in OR 6.5 (95% Cl 0.8 to 96; p=0.08). In the EVAR group, 60% (9/15) had complications; in the group with open surgery, the complication rate was 85% (22/26; p=0.13). Conclusions: It is possible to treat rAAA with EVAR. Hypotensive patients can, at least initially, be operated under local anesthesia to stabilize blood pressure utilizing a percutaneously inserted occlusion balloon. There was a trend in our study for reduced mortality and morbidity with EVAR, but further studies are required to conclude whether EVAR significantly increases survival and reduces complications.
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页码:548 / 555
页数:8
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