Linking Rap to cell adhesion

被引：391

作者：

Bos, JL

机构：

[1] UMC Utrecht, Dept Physiol Chem, NL-3584 CG Utrecht, Netherlands

[2] UMC Utrecht, Ctr Biomed Genet, NL-3584 CG Utrecht, Netherlands

来源：

CURRENT OPINION IN CELL BIOLOGY | 2005年 / 17卷 / 02期

关键词：

D O I：

10.1016/j.ceb.2005.02.009

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The small GTPase Rap1 is involved in several aspects of cell adhesion, including integrin-mediated cell adhesion and cadherin-mediated cell junction formation. Recently, several effector proteins for Rap1 have been identified providing a clear link between Rap1 and actin dynamics. Furthermore, evidence is accumulating that Rap1 functions in the spatial and temporal control of cell polarity.

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页码：123 / 128

页数：6

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