Development of novel cell-permeable DNA sensitive dyes using combinatorial synthesis and cell-based screening

被引：71

作者：

Lee, JW

Jung, M

Rosania, GR

Chang, YT ^{[1
]}

机构：

[1] NYU, Dept Chem, New York, NY 10003 USA

[2] Univ Michigan, Coll Pharm, Dept Pharmaceut, Ann Arbor, MI 48109 USA

来源：

CHEMICAL COMMUNICATIONS | 2003年 / 15期

关键词：

D O I：

10.1039/b303960a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A novel cell-permeable DNA fluorescence sensor was developed based on combinatorially-created styryl dyes and cell-based localization screening.

引用

页码：1852 / 1853

页数：2

共 16 条

[1] Synthesis of a hoechst 32258 analogue amino acid building block for direct incorporation of a fluorescent, high-affinity DNA binding motif into peptides [J].

Behrens, C ;

Harrit, N ;

Nielsen, PE .

BIOCONJUGATE CHEMISTRY, 2001, 12 (06) :1021-1027

[2] Use of SYTOX green dye in the flow cytometric analysis of bacterial phagocytosis [J].

Gaforio, JJ ;

Serrano, MJ ;

Ortega, E ;

Algarra, I ;

de Cienfuegos, GA .

CYTOMETRY, 2002, 48 (02) :93-96

[3] A FLUORESCENCE STUDY OF THE BINDING OF HOECHST-33258 AND DAPI TO HALOGENATED DNAS [J].

HARD, T ;

FAN, P ;

KEARNS, DR .

PHOTOCHEMISTRY AND PHOTOBIOLOGY, 1990, 51 (01) :77-86

[4]

HAUGLAND RP, 2002, NUCL ACID DETECTION, P265

[5] Fluorescence microplate-based assay for tumor necrosis factor activity using SYTOX green stain [J].

Jones, LJ ;

Singer, VL .

ANALYTICAL BIOCHEMISTRY, 2001, 293 (01) :8-15

[6] SIMPLE, RAPID, AND SENSITIVE DNA ASSAY PROCEDURE [J].

LABARCA, C ;

PAIGEN, K .

ANALYTICAL BIOCHEMISTRY, 1980, 102 (02) :344-352

[7] ETHIDIUM-BROMIDE AS A PROBE OF CHROMATIN STRUCTURE [J].

LAWRENCE, JJ ;

LOUIS, M .

FEBS LETTERS, 1974, 40 (01) :9-12

[8]

Lebaron P, 1998, APPL ENVIRON MICROB, V64, P2697

[9] A FLUORESCENT COMPLEX BETWEEN ETHIDIUM BROMIDE AND NUCLEIC ACIDS - PHYSICAL-CHEMICAL CHARACTERIZATION [J].

LEPECQ, JB ;

PAOLETTI, C .

JOURNAL OF MOLECULAR BIOLOGY, 1967, 27 (01) :87-+

[10]

MATUSUI M, 1992, B CHEM SOC JPN, V65, P71

← 1 2 →