Circadian regulation of the light input pathway in Neurospora crassa

被引：102

作者：

Merrow, M

Franchi, L

Dragovic, Z

Görl, M

Johnson, J

Brunner, M

Macino, G ^{[1
]}

Roenneberg, T

机构：

[1] Univ Rome, Dipartimento Biotecnol Cellulari & Ematol, I-00185 Rome, Italy

[2] Univ Munich, Inst Med Psychol, D-80336 Munich, Germany

[3] Univ Munich, Inst Physiol Chem, D-80336 Munich, Germany

[4] Univ Munich, Inst Immunol, D-80336 Munich, Germany

[5] NYU, Dept Biol, New York, NY 10003 USA

来源：

EMBO JOURNAL | 2001年 / 20卷 / 03期

关键词：

circadian; frequency; light; Neurosporal; white collar;

D O I：

10.1093/emboj/20.3.307

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

FREQUENCY (FRQ) is a critical element of the circadian system of Neurospora, The white collar genes are important both for light reception and circadian function. We show that the responsiveness of the light input pathway is circadianly regulated. This circadian modulation extends to light-inducible components and functions that are not rhythmic themselves in constant conditions. FRQ interacts genetically and physically with WHITE COLLAR-I, and physically with WHITE COLLAR-2. These findings begin to address how components of the circadian system interact with basic cellular functions, in this case with sensory transduction.

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页码：307 / 315

页数：9

相关论文

共 54 条

[1] CIRCADIAN CLOCK LOCUS FREQUENCY - PROTEIN ENCODED BY A SINGLE OPEN READING FRAME DEFINES PERIOD LENGTH AND TEMPERATURE COMPENSATION [J].

ARONSON, BD ;

JOHNSON, KA ;

DUNLAP, JC .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1994, 91 (16) :7683-7687

[2] NEGATIVE FEEDBACK DEFINING A CIRCADIAN CLOCK - AUTOREGULATION OF THE CLOCK GENE-FREQUENCY [J].

ARONSON, BD ;

JOHNSON, KA ;

LOROS, JJ ;

DUNLAP, JC .

SCIENCE, 1994, 263 (5153) :1578-1584

[3] Involvement of protein kinase C in the response of Neurospora crassa to blue light [J].

Arpaia, G ;

Cerri, F ;

Baima, S ;

Macino, G .

MOLECULAR AND GENERAL GENETICS, 1999, 262 (02) :314-322

[4] THE INTERPLAY OF LIGHT AND THE CIRCADIAN CLOCK - INDEPENDENT DUAL REGULATION OF CLOCK-CONTROLLED GENE CCG-2(EAS) [J].

ARPAIA, G ;

LOROS, JJ ;

DUNLAP, JC ;

MORELLI, G ;

MACINO, G .

PLANT PHYSIOLOGY, 1993, 102 (04) :1299-1305

[5] LIGHT INDUCTION OF THE CLOCK-CONTROLLED GENE CCG-1 IS NOT TRANSDUCED THROUGH THE CIRCADIAN CLOCK IN NEUROSPORA-CRASSA [J].

ARPAIA, G ;

LOROS, JJ ;

DUNLAP, JC ;

MORELLI, G ;

MACINO, G .

MOLECULAR & GENERAL GENETICS, 1995, 247 (02) :157-163

[6] Circadian regulation of a Drosophila homolog of the mammalian Clock gene:: PER and TIM function as positive regulators [J].

Bae, K ;

Lee, C ;

Sidote, D ;

Chuang, KY ;

Edery, I .

MOLECULAR AND CELLULAR BIOLOGY, 1998, 18 (10) :6142-6151

[7] White collar-1, a central regulator of blue light responses in Neurospora, is a zinc finger protein [J].

Ballario, P ;

Vittorioso, P ;

Magrelli, A ;

Talora, C ;

Cabibbo, A ;

Macino, G .

EMBO JOURNAL, 1996, 15 (07) :1650-1657

[8] Accuracy of circadian entrainment under fluctuating light conditions: Contributions of phase and period responses [J].

Beersma, DGM ;

Daan, S ;

Hut, RA .

JOURNAL OF BIOLOGICAL RHYTHMS, 1999, 14 (04) :320-329

[9] The circadian clock controls the expression pattern of the circadian input photoreceptor, phytochrome B [J].

Bognár, LK ;

Hall, A ;

Adám, É ;

Thain, SC ;

Nagy, F ;

Millar, AJ .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (25) :14652-14657

[10] Light-dependent sequestration of TIMELESS by CRYPTOCHROME [J].

Ceriani, MF ;

Darlington, TK ;

Staknis, D ;

Más, P ;

Petti, AA ;

Weitz, CJ ;

Kay, SA .

SCIENCE, 1999, 285 (5427) :553-556

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