The cadherin superfamily and dendrite development

被引:22
作者
Ye, B
Jan, YN [1 ]
机构
[1] Univ Calif San Francisco, Howard Hughes Med Inst, Dept Physiol, San Francisco, CA 94143 USA
[2] Univ Calif San Francisco, Howard Hughes Med Inst, Dept Biochem & Biophys, San Francisco, CA 94143 USA
关键词
D O I
10.1016/j.tcb.2004.12.003
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Dendrite morphogenesis is a highly dynamic process that involves constant extension and retraction of branches, and stabilization of these dynamics has pivotal roles in determining the number and length of branches. The classic cadherin N-cadherin is involved in stabilization of dendritic spines and branches. Recent work in mammals by Shima et A, and earlier work in Drosophila by Gao et A and Sweeney et A have determined the presence of a non-classic, seven-pass transmembrane cadherin in this process.
引用
收藏
页码:64 / 67
页数:4
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