Does the permanent portacaval shunt for a small-for-size graft in a living donor liver transplantation do more harm than good?

被引:40
作者
Oura, T. [1 ]
Taniguchi, M. [1 ]
Shimamura, T. [2 ]
Suzuki, T. [3 ]
Yamashita, K. [1 ]
Uno, M. [1 ]
Goto, R. [1 ]
Watanabe, M. [1 ]
Kamiyama, T. [1 ]
Matsushita, M. [1 ]
Furukawa, H. [3 ]
Todo, S. [1 ]
机构
[1] Hokkaido Univ, Grad Sch Med, Dept Gen Surg, Sapporo, Hokkaido, Japan
[2] Hokkaido Univ, Grad Sch Med, Div Organ Transplantat, Sapporo, Hokkaido, Japan
[3] Hokkaido Univ, Grad Sch Med, Dept Organ Transplantat & Regenerat, Sapporo, Hokkaido, Japan
关键词
living donor liver transplantation; portacaval shunt; portal venous inflow; small for size graft; transient PC shunt;
D O I
10.1111/j.1600-6143.2007.02045.x
中图分类号
R61 [外科手术学];
学科分类号
摘要
In order to obviate a small-for-size graft syndrome (SFSGS), a portacaval (PC) shunt had been considered in a case of adult-to-adult living donor liver transplantation (AA-LDLT). In a recent AA-LDLT case, we adopted the PC shunt to resolve SFSGS; however, graft atrophy was observed in the late period of LDLT, thereby resulting in liver dysfunction. Due to the surgical closure of the PC shunt at 11 months post-LDLT, the graft regenerated gradually and resulted in the recovery of the liver function. This experience indicates that the portacaval shunt would overcome SFSGS in the early period of LDLT, while it would cause the graft atrophy and the graft dysfunction in the late period of LDLT.
引用
收藏
页码:250 / 252
页数:3
相关论文
共 18 条
[1]   Portal vein pressure is the key for successful liver transplantation of an extremely small graft in the pig model [J].
Asakura, T ;
Ohkohchi, N ;
Orii, T ;
Koyamada, N ;
Tsukamoto, S ;
Sato, M ;
Enomoto, Y ;
Usuda, M ;
Satomi, S .
TRANSPLANT INTERNATIONAL, 2003, 16 (06) :376-382
[2]   Small-for-size partial liver graft in an adult recipient;: a new transplant technique [J].
Boillot, O ;
Delafosse, B ;
Méchet, I ;
Boucaud, C ;
Pouyet, M .
LANCET, 2002, 359 (9304) :406-407
[3]   Functional analysis of grafts from living donors - Implications for the treatment of older recipients [J].
Emond, JC ;
Renz, JF ;
Ferrell, LD ;
Rosenthal, P ;
Lim, RC ;
Roberts, JP ;
Lake, JR ;
Ascher, NL .
ANNALS OF SURGERY, 1996, 224 (04) :544-552
[4]  
Ferrell LD, 1996, ANN SURG, V224, P552
[5]   Right lobe graft in living donor liver transplantation [J].
Inomata, Y ;
Uemoto, S ;
Asonuma, K ;
Egawa, H ;
Kiuchi, T ;
Fujita, S ;
Hayashi, M ;
Kawashima, M ;
Tanaka, K .
TRANSPLANTATION, 2000, 69 (02) :258-264
[6]   Changes in portal venous pressure in the early phase after living-donor liver transplantation: Pathogenesis and clinical implications [J].
Ito, T ;
Kiuchi, T ;
Yamamoto, H ;
Oike, F ;
Ogura, Y ;
Fujimoto, Y ;
Hirohashi, K ;
Tanaka, K .
TRANSPLANTATION, 2003, 75 (08) :1313-1317
[7]   Impact of right lobe with middle hepatic vein graft in living-donor liver transplantation [J].
Kasahara, M ;
Takada, Y ;
Fujimoto, Y ;
Ogura, Y ;
Ogawa, K ;
Uryuhara, K ;
Yonekawa, Y ;
Ueda, M ;
Egawa, H ;
Tanaka, K .
AMERICAN JOURNAL OF TRANSPLANTATION, 2005, 5 (06) :1339-1346
[8]   Living related liver transplantation in adults [J].
Kawasaki, S ;
Makuuchi, M ;
Matsunami, H ;
Hashikura, Y ;
Ikegami, T ;
Nakazawa, Y ;
Chisuwa, H ;
Terada, M ;
Miyagawa, S .
ANNALS OF SURGERY, 1998, 227 (02) :269-274
[9]   Porcine partial liver transplantation: A novel model of the "small-for-size" liver graft [J].
Kelly, DM ;
Demetris, AJ ;
Fung, JJ ;
Marcos, A ;
Zhu, Y ;
Subbotin, V ;
Yin, L ;
Totsuka, E ;
Ishii, T ;
Lee, MC ;
Gutierrez, J ;
Costa, G ;
Venkataraman, R ;
Madariaga, JR .
LIVER TRANSPLANTATION, 2004, 10 (02) :253-263
[10]   Impact of graft size mismatching on graft prognosis in liver transplantation from living donors [J].
Kiuchi, T ;
Kasahara, M ;
Uryuhara, K ;
Inomata, Y ;
Uemoto, S ;
Asonuma, K ;
Egawa, H ;
Fujita, S ;
Hayashi, M ;
Tanaka, K .
TRANSPLANTATION, 1999, 67 (02) :321-327