Nanog:: A new recruit to the embryonic stem cell orchestra

被引：110

作者：

Cavaleri, F ^{[1
]}

Schöler, HR ^{[1
]}

机构：

[1] Univ Penn, New Bolton Ctr, Sch Vet Med, Ctr Anim Transgenesis & Germ Cell Res, Kennett Sq, PA 19348 USA

来源：

CELL | 2003年 / 113卷 / 05期

关键词：

D O I：

10.1016/S0092-8674(03)00394-5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

In this issue of Cell, Chambers et al. (2003) and Mitsui et al. (2003) add a new transcriptional operating system to the known Oct4 and Stat3 systems required for early embryonal stem cell potency and self-renewal. Nanog, a homeobox transcription factor, plays a crucial role in the second embryonic cell fate specification following formation of the blastocyst.

引用

页码：551 / 552

页数：2

共 11 条

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