Ethylene oxide sterilization of autologous bone flaps following decompressive craniectomy

被引:21
作者
Missori, P [1 ]
Polli, FM [1 ]
Rastelli, E [1 ]
Baiocchi, P [1 ]
Artizzu, S [1 ]
Rocchi, G [1 ]
Salvati, M [1 ]
Paolini, S [1 ]
Delfini, R [1 ]
机构
[1] Univ Roma La Sapienza, Dept Clin Med, Rome, Italy
关键词
bone; craniectomy; ethylene oxide; surgery;
D O I
10.1007/s00701-003-0118-y
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Introduction. In patients undergoing decompressive craniectomy, the bone flap is temporarily preserved either in the subcutaneous tissue of the patient or frozen. However, there are some drawbacks related to these methods. Material and methods. In 16 patients in whom the bone flap was removed for decompressive craniectomy, the bone was firstly washed in hydrogen peroxide and then placed in hermetically-scaled bags and sterilized using ethylene oxide. The bone was repositioned after an average period of 4.3 months. Results. One patient sustained an infection of the surgical wound which required permanent exclusion of the bone flap. In all the others, esthetic and functional results were good after an average follow-up of 20 months. Control CT-scan of the bone flap demonstrated preservation of its structural features with fusion of the bone margins and revitalization of the flap. On MRI a subdural space was again visible. Conclusions. Sterilization of the bone flap with ethylene oxide in patients undergoing decompressive craniectomy avoids some of the drawbacks related to the techniques currently used. The easiness, low cost, good aesthetic and functional results of this procedure make it a valid alternative to other techniques for preservation of autologous bone in decompressive craniectomies.
引用
收藏
页码:899 / 903
页数:5
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