A loss of functional spinal alpha motor neurons in amyotrophic lateral sclerosis

被引：20

作者：

Arasaki, K ^{[1
]}

Tamaki, N ^{[1
]}

机构：

[1] Nippon Telegraph & Tel Corp, Kanto Teishin Hosp, Dept Neurol, EMG EEG Lab,Shinagawa Ku, Tokyo 1410022, Japan

来源：

NEUROLOGY | 1998年 / 51卷 / 02期

关键词：

D O I：

10.1212/WNL.51.2.603

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

We obtained motor unit number estimates (MUNEs) of the hypothenar and the extensor digitorum brevis muscles in ALS patients by our new technique. One year after symptom onset, the MUNEs had decreased to +/- 30% of normal. Accordingly, we suggest that 70% of functional spinal alpha motor neurons are lost in the first post-onset year in ALS.

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收藏

页码：603 / 605

页数：3

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