Epithelial transcytosis of immunoglobulins

被引：58

作者：

Hunziker, W ^{[1
]}

Kraehenbuhl, JP

机构：

[1] Univ Lausanne, Inst Biochem, BIL Res Ctr, CH-1066 Epalinges, Switzerland

[2] Swiss Inst Canc Res, BIL Res Ctr, CH-1066 Epalinges, Switzerland

来源：

JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA | 1998年 / 3卷 / 03期

关键词：

antigen presentation; Fc receptor; homing; immunity; membrane traffic;

D O I：

10.1023/A:1018715511178

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Transcytosis plays a central role in the immunological functions of epithelia, including the sampling of antigens that enter the body via the digestive, respiratory and urogenital tracts and their presentation to underlying lymphoid tissues, the secretion of specific immunoglobulins required for the immune protection of mucosal surfaces and the transfer of maternal immunoglobulins to the fetus or newborn, providing the latter with passive immunity for the first weeks of independent life.

引用

页码：287 / 302

页数：16

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