The mitochondrial permeability transition pore complex as a pharmacological target. An introduction

被引：28

作者：

Kroemer, G ^{[1
]}

机构：

[1] Inst Gustave Roussy, CNRS, UMR 8125, F-94805 Villejuif, France

来源：

CURRENT MEDICINAL CHEMISTRY | 2003年 / 10卷 / 16期

关键词：

D O I：

10.2174/0929867033457232

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：1469 / 1472

页数：4

共 44 条

[1]

Banerjee D, 2001, Curr Opin Investig Drugs, V2, P574

[2] Adenine nucleotide translocase-1, a component of the permeability transition pore, can dominantly induce apoptosis [J].

Bauer, MKA ;

Schubert, A ;

Rocks, O ;

Grimm, S .

JOURNAL OF CELL BIOLOGY, 1999, 147 (07) :1493-1501

[3] Adenine nucleotide translocator mediates the mitochondrial membrane permeabilization induced by lonidamine, arsenite and CD437 [J].

Belzacq, AS ;

El Hamel, C ;

Vieira, HLA ;

Cohen, I ;

Haouzi, D ;

Métivier, D ;

Marchetti, P ;

Brenner, C ;

Kroemer, G .

ONCOGENE, 2001, 20 (52) :7579-7587

[4] Complexes between kinases, mitochondrial porin and adenylate translocator in rat brain resemble the permeability transition pore [J].

Beutner, G ;

Ruck, A ;

Riede, B ;

Welte, W ;

Brdiczka, D .

FEBS LETTERS, 1996, 396 (2-3) :189-195

[5] Benzodiazepine-induced superoxide signals B cell apoptosis: mechanistic insight and potential therapeutic utility [J].

Blatt, NB ;

Bednarski, JJ ;

Warner, RE ;

Leonetti, F ;

Johnson, KM ;

Boitano, A ;

Yung, R ;

Richardson, BC ;

Johnson, KJ ;

Ellman, JA ;

Opipari, AW ;

Glick, GD .

JOURNAL OF CLINICAL INVESTIGATION, 2002, 110 (08) :1123-1132

[6] Bcl-2 and Bax regulate the channel activity of the mitochondrial adenine nucleotide translocator [J].

Brenner, C ;

Cadiou, H ;

Vieira, HLA ;

Zamzami, N ;

Marzo, I ;

Xie, ZH ;

Leber, B ;

Andrews, D ;

Duclohier, H ;

Reed, JC ;

Kroemer, G .

ONCOGENE, 2000, 19 (03) :329-336

[7] Involvement of peripheral benzodiazepine receptors in the protection of hematopoietic cells against oxygen radical damage [J].

Carayon, P ;

Portier, M ;

Dussossoy, D ;

Bord, A ;

Petitpretre, G ;

Canat, X ;

LeFur, G ;

Casellas, P .

BLOOD, 1996, 87 (08) :3170-3178

[8] Calpain and mitochondria in ischemia/reperfusion injury [J].

Chen, M ;

Won, DJ ;

Krajewski, S ;

Gottlieb, RA .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2002, 277 (32) :29181-29186

[9]

CLARKE SJ, 2002, J BIOL CHEM, V2, P2

[10] Cyclophilin-D binds strongly to complexes of the voltage-dependent anion channel and the adenine nucleotide translocase to form the permeability transition pore [J].

Crompton, M ;

Virji, S ;

Ward, JM .

EUROPEAN JOURNAL OF BIOCHEMISTRY, 1998, 258 (02) :729-735

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