Expression pattern of the drm/gremlin gene during chicken embryonic development

被引：21

作者：

Bardot, B ^{[1
]}

Lecoin, L ^{[1
]}

Huillard, E ^{[1
]}

Calothy, G ^{[1
]}

Marx, M ^{[1
]}

机构：

[1] Ctr Univ Orsay, Inst Curie, UMR 146 CNRS, F-91405 Orsay, France

来源：

MECHANISMS OF DEVELOPMENT | 2001年 / 101卷 / 1-2期

关键词：

drm; gremlin; BMP; somites; myotome; dermatome; branchial arches; chicken embryo;

D O I：

10.1016/S0925-4773(00)00571-2

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The drm gene encodes a cystine knot-containing secreted and cell membrane-associated glycoprotein shown to be an antagonist of BMPs. Drm was recently reported to play a crucial role in limb bud development, by its capacity to bind BMPs. Here, we have studied the expression pattern of drm transcripts during chicken development, by using whole-mount in situ hybridization. We show that, from stage 22HH to stage 26HH, in addition to limb buds, drm is expressed in cephalic neural crest-derived branchial arches I, II and III, in the medio-dorsal lip of the myotome and in the superficial dermatome. (C) 2001 Elsevier science ireland Ltd. All rights reserved.

引用

页码：263 / 265

页数：3

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