The biochemistry of the visual cycle

被引：139

作者：

Rando, RR ^{[1
]}

机构：

[1] Harvard Univ, Sch Med, Dept Biol Chem & Mol Pharmacol, Boston, MA 02115 USA

来源：

CHEMICAL REVIEWS | 2001年 / 101卷 / 07期

关键词：

D O I：

10.1021/cr960141c

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The biochemistry of vertebrate visual cycle and the actual biological site of isomerization present in the retinal pigment epithelium (RPE) were investigated. The processing of vitamin A in the retina and its reisomerization in the RPE was studied. The enzymes involved in the visual cycle including lecithin retinol acyl transferase (LRAT) were discussed. The influence of light intensity on the biosynthesis of 11-cis-retinal and the associated regulatory mechanisms were also described.

引用

页码：1881 / 1896

页数：16

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