Auger-electron spectra of radionuclides for therapy and diagnostics

被引:44
作者
Stepanek, J [1 ]
Larsson, B [1 ]
Weinreich, R [1 ]
机构
[1] UNIV ZURICH,INST MED RADIOBIOL,CH-8006 ZURICH,SWITZERLAND
关键词
D O I
10.3109/02841869609104038
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
The present paper documents the calculation of radiation spectra and of radial dose distribution around a point source for 24 selected radionculides. The radionculides were ordered into three groups: Nuclides potentially useful for therapy by emission of Auger electrons: Cr-51, Cu-64, Ga-67, Se-73, Se-75, Br-77, Br-80, Tc-94, Tc-99m, In-114m, In-115m, I-123, I-124, I-125, Tm-167, Pt-193m, and Pt-195m, nuclides potentially useful for therapy by alpha-particles with additional emission of Auger electrons: Bi-212, At-211 and Fm-255, and nuclides potentially useful for electron Auger-therapy with simultaneous PET diagnosis: Se-73, Tc-94 and I-124. The calculations imply strongly the development of labelled DNA-seeking compounds useful as carrier for the Auger- and Coster-Kronig electron-emitting radionuclides.
引用
收藏
页码:863 / 868
页数:6
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