Multisignall chemosensor for Cr3+ and its application in bioimaging

被引:238
作者
Huang, Kewei
Yang, Hong
Zhou, Zhiguo
Yu, Mengxiao
Li, Fuyou [1 ]
Gao, Xia
Yi, Tao
Huang, Chunhui
机构
[1] Fudan Univ, Dept Chem, Shanghai 200433, Peoples R China
关键词
D O I
10.1021/ol800778a
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A multisignal sensor based on rhodamine B with a ferrocene substituent (FD7) has been developed as a highly sensitive chemosensor for Cr3+. A prominent fluorescence enhancement was found in the presence of Cr3+, which was accompanied by changes in the absorption spectrum and the electrochemical parameters. Furthermore, by means of confocal laser scanning microscopy experiments, it has been demonstrated that FD7 can be used as a fluorescent probe for monitoring Cr3+ in living cells.
引用
收藏
页码:2557 / 2560
页数:4
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共 37 条
[1]   Meeting of the minds: Metalloneurochemistry [J].
Burdette, SC ;
Lippard, SJ .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2003, 100 (07) :3605-3610
[2]   Highly selective chromogenic and redox or fluorescent sensors of Hg2+ in aqueous environment based on 1,4-disubstituted azines [J].
Caballero, A ;
Martínez, R ;
Lloveras, V ;
Ratera, I ;
Vidal-Gancedo, J ;
Wurst, K ;
Tárraga, A ;
Molina, P ;
Veciana, J .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2005, 127 (45) :15666-15667
[3]   An electroactive nitrogen-rich [4.4]ferrocenophane displaying redox-switchable behavior:: Selective sensing, complexation, and decomplexation of Mg2+ ions [J].
Caballero, A ;
Lloveras, V ;
Tárraga, A ;
Espinosa, A ;
Velasco, MD ;
Vidal-Gancedo, J ;
Rovira, C ;
Wurst, K ;
Molina, P ;
Veciana, J .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2005, 44 (13) :1977-1981
[4]   A tautomeric zinc sensor for ratiometric fluorescence imaging: Application to nitric oxide-induced release of intracellular zinc [J].
Chang, CJ ;
Jaworski, J ;
Nolan, EM ;
Sheng, M ;
Lippard, SJ .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2004, 101 (05) :1129-1134
[5]   A long-wavelength fluorescent chemodosimeter selective for Cu(II) ion in water [J].
Dujols, V ;
Ford, F ;
Czarnik, AW .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1997, 119 (31) :7386-7387
[6]   8-Hydroxyquinoline derivatives as fluorescent sensors for magnesium in living cells [J].
Farruggia, G ;
Iotti, S ;
Prodi, L ;
Montalti, M ;
Zaccheroni, N ;
Savage, PB ;
Trapani, V ;
Sale, P ;
Wolf, FI .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2006, 128 (01) :344-350
[7]   A selective fluorescent sensor for detecting lead in living cells [J].
He, Qiwen ;
Miller, Evan W. ;
Wong, Audrey P. ;
Chang, Christopher J. .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2006, 128 (29) :9316-9317
[8]   Design and synthesis of zinc-selective chelators for extracellular applications [J].
Kawabata, E ;
Kikuchi, K ;
Urano, Y ;
Kojima, H ;
Odani, A ;
Nagano, T .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2005, 127 (03) :818-819
[9]   Zinc sensing for cellular application [J].
Kikuchi, K ;
Komatsu, K ;
Nagano, T .
CURRENT OPINION IN CHEMICAL BIOLOGY, 2004, 8 (02) :182-191
[10]   In vivo monitoring of mercury ions using a rhodamine-based molecular probe [J].
Ko, Sung-Kyun ;
Yang, Young-Keun ;
Tae, Jinsung ;
Shin, Injae .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2006, 128 (43) :14150-14155