Nicotine augmentation for refractory obsessive-compulsive disorder. A case report

被引：25

作者：

Pasquini, M ^{[1
]}

Garavini, A ^{[1
]}

Biondi, M ^{[1
]}

机构：

[1] Univ Roma La Sapienza, Psychiat Clin 3, I-00185 Rome, Italy

来源：

PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY | 2005年 / 29卷 / 01期

关键词：

obsessive-compulsive disorder; nicotine; glutamatergic transmission; memory for actions;

D O I：

10.1016/j.pnpbp.2004.08.011

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The authors present a case of obsessive-compulsive disorder (OCD) resistant to conventional treatments. which improved following nicotine augmentation administered as 4 mg chewing gum. The role of acetylcholine in the pathophysiology of OCD is not clear. The authors discuss the effect of nicotine on memory for actions. (C) 2004 Elsevier Inc. All rights reserved.

引用

页码：157 / 159

页数：3

共 17 条

[1] fMRI of neuronal activation with symptom provocation in unmedicated patients with obsessive compulsive disorder
Adler, CM
McDonough-Ryan, P
Sax, KW
Holland, SK
Arndt, S
Strakowski, SM
[J]. JOURNAL OF PSYCHIATRIC RESEARCH, 2000, 34 (4-5) : 317 - 324
[2] Tc-99m HMPAO brain perfusion SPECT in drug-free obsessive-compulsive patients without depression
Alptekin, K
Degirmenci, B
Kivircik, B
Durak, H
Yemez, B
Derebek, E
Tunca, Z
[J]. PSYCHIATRY RESEARCH-NEUROIMAGING, 2001, 107 (01) : 51 - 56
[3] Neuronal nicotinic receptor and psychiatric disorders: Functional and behavioral effects of nicotine
Araki, H
Suemaru, K
Gomita, Y
[J]. JAPANESE JOURNAL OF PHARMACOLOGY, 2002, 88 (02) : 133 - 138
[4] Brain metabolic changes during cigarette craving
Brody, AL
Mandelkern, MA
London, ED
Childress, AR
Lee, GS
Bota, RG
Ho, ML
Saxena, S
Baxter, LR
Madsen, D
Jarvik, ME
[J]. ARCHIVES OF GENERAL PSYCHIATRY, 2002, 59 (12) : 1162 - 1172
[5] On the role of prefrontal cortex glutamate for the antithetical phenomenology of obsessive compulsive disorder and attention deficit hyperactivity disorder
Carlsson, ML
[J]. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY, 2001, 25 (01) : 5 - 26
[6] Facilitation of glutamatergic neurotransmission by presynaptic nicotinic acetylcholine receptors
Girod, R
Barazangi, N
McGehee, D
Role, LW
[J]. NEUROPHARMACOLOGY, 2000, 39 (13) : 2715 - 2725
[7] The role of N-methyl-D-aspartate (NMDA) receptor-mediated neurotransmission in the pathophysiology and therapeutics of psychiatric syndromes
Heresco-Levy, U
Javitt, DC
[J]. EUROPEAN NEUROPSYCHOPHARMACOLOGY, 1998, 8 (02) : 141 - 152
[8] Evidence for a complex influence of nicotinic acetylcholine receptors on hippocampal serotonin release
Kenny, PJ
File, SE
Neal, MJ
[J]. JOURNAL OF NEUROCHEMISTRY, 2000, 75 (06) : 2409 - 2414
[9] Synaptic mechanisms underlie nicotine-induced excitability of brain reward areas
Mansvelder, HD
Keath, JR
McGehee, DS
[J]. NEURON, 2002, 33 (06) : 905 - 919
[10] Okasha A, 2000, ACTA PSYCHIAT SCAND, V101, P281, DOI 10.1111/j.1600-0447.2000.tb10926.x

← 1 2 →