Influence of the hydrodynamic environment on quorum sensing in Pseudomonas aeruginosa biofilms

被引:82
作者
Kirisits, Mary Jo
Margolis, Jeffrey J.
Purevdorj-Gage, Boloroo L.
Vaughan, Benjamin
Chopp, David L.
Stoodley, Paul
Parsek, Matthew R.
机构
[1] Univ Texas Austin, Dept Civil Architectural & Environm Engn, Austin, TX 78712 USA
[2] Univ Washington, Sch Med, Dept Microbiol, Seattle, WA 98195 USA
[3] Stanford Univ, Sch Med, Dept Microbiol & Immunol, Stanford, CA 94305 USA
[4] Montana State Univ, Ctr Biofilm Engn, Bozeman, MT 59717 USA
[5] Northwestern Univ, Dept Engn Sci & Appl Math, Evanston, IL 60208 USA
[6] Ctr Genom Sci, Pittsburgh, PA 15212 USA
[7] Univ Washington, Dept Microbiol, Seattle, WA 98195 USA
关键词
D O I
10.1128/JB.01040-07
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
We provide experimental and modeling evidence that the hydrodynamic environment can impact quorum sensing (QS) in a Pseudomonas aeruginosa biofilm. The amount of biofilm biomass required for full QS induction of the population increased as the flow rate increased.
引用
收藏
页码:8357 / 8360
页数:4
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