Isolation and initial characterization of the mouse Dnmt3/gene

被引：53

作者：

Aapola, U

Lyle, R

Krohn, K

Antonarakis, SE

Peterson, P

机构：

[1] Tampere Univ, Inst Med Technol, Dept Pathol, Tampere 33014, Finland

[2] Tampere Univ Hosp, Tampere, Finland

[3] Univ Hosp Geneva, Div Med Genet, Geneva, Switzerland

[4] Univ Geneva, Sch Med, Div Med Genet, CH-1211 Geneva, Switzerland

来源：

CYTOGENETICS AND CELL GENETICS | 2001年 / 92卷 / 1-2期

关键词：

D O I：

10.1159/000056881

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

We have isolated and sequenced the mouse zinc finger gene, Dnmt3l (DNA cytosine-5-methyltransferase 3-like), on mouse chromosome 10, showing similarity to members of the DNMT3/Dnmt3 family. The Dnmt3l protein contains an ADD zinc finger. which Dnmt3l shares with Other Dnmt3 family members and Atrx. RT-PCR analysis showed Dnmt3l expression in testis, thymus, ovary, and heart, as well as in 7-day, 15-day, and 17-day mouse embryos. Copyright (C) 2001 S. Karger AG, Basel.

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页码：122 / 126

页数：5

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