Inhibitory activity of lignan components from the flower buds of Magnoliae fargesii on the expression of cell adhesion molecules

被引：17

作者：

Ahn, KS ^{[1
]}

Jung, KY ^{[1
]}

Kim, JH ^{[1
]}

Oh, SR ^{[1
]}

Lee, HK ^{[1
]}

机构：

[1] Korea Res Inst Biosci & Biotechnol, Immunomodulator Res Lab, Taejon 305600, South Korea

来源：

BIOLOGICAL & PHARMACEUTICAL BULLETIN | 2001年 / 24卷 / 09期

关键词：

intercellular adhesion molecule-1; vascular cell adhesion molecule-1; Magnoliae fargesii; lignan;

D O I：

10.1248/bpb.24.1085

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Inhibitory activity of lignans isolated from Magnoliae fargesii CHENG on cell adhesion molecules on the surface of THP-1 human monocytic cell lines were investigated. Among 16 lignan components tested, six displayed relatively potent inhibitory activity on the expression of both intercellular adhesion molecule-1 (ICAM-1) and vascular cell adhesion molecule-1 (VCAM-1).

引用

页码：1085 / 1087

页数：3

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