Role of antioxidants and trace elements in health and immunity of transition dairy cows

被引:381
作者
Spears, Jerry W. [1 ,2 ]
Weiss, William P. [3 ]
机构
[1] N Carolina State Univ, Dept Anim Sci, Raleigh, NC 27695 USA
[2] N Carolina State Univ, Interdepartmental Nutr Program, Raleigh, NC 27695 USA
[3] Ohio State Univ, Dept Anim Sci, Wooster, OH 44691 USA
关键词
Transition cow; Vitamin E; Selenium; Coppe; Zinc; Chromium; beta-Carotene;
D O I
10.1016/j.tvjl.2007.12.015
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
A number of antioxidants and trace minerals have important roles in immune function and may affect health in transition dairy cows. Vitamin E and R-carotene are important cellular antioxidants. Selenium (Se) is involved in the antioxidant system via its role in the enzyme glutathione peroxidase. Inadequate dietary vitamin E or Se decreases neutrophil function during the perpariturient period. Supplementation of vitamin E and/or Se has reduced the incidence of mastitis and retained placenta, and reduced duration of clinical symptoms of mastitis in some experiments. Research has indicated that beta-carotene supplementation may enhance immunity and reduce the incidence of retained placenta and metritis in dairy cows. Marginal copper deficiency resulted in reduced neutrophil killing and decreased interferon production by mononuclear cells. Copper supplementation of a diet marginal in copper reduced the peak clinical response during experimental Escherichia coli mastitis. Limited research indicated that chromium supplementation during the transition period may increase immunity and reduce the incidence of retained placenta. (C) 2008 Elsevier Ltd. All rights reserved.
引用
收藏
页码:70 / 76
页数:7
相关论文
共 69 条
[1]  
Allison RD, 2000, VET REC, V147, P703
[2]  
[Anonymous], 2001, NATL ACAD SCI
[3]  
AZIZ ES, 1984, AM J VET RES, V45, P1715
[4]   EFFECT OF VITAMIN-E ON INCIDENCE OF MASTITIS IN DAIRY-CATTLE [J].
BATRA, TR ;
HIDIROGLOU, M ;
SMITH, MW .
CANADIAN JOURNAL OF ANIMAL SCIENCE, 1992, 72 (02) :287-297
[5]  
BROADLEY C, 1989, AM J PATHOL, V135, P647
[6]   EFFECTS OF SUPPLEMENTAL CHROMIUM ON IMMUNE-RESPONSES OF PERIPARTURIENT AND EARLY LACTATION DAIRY-COWS [J].
BURTON, JL ;
MALLARD, BA ;
MOWAT, DN .
JOURNAL OF ANIMAL SCIENCE, 1993, 71 (06) :1532-1539
[7]   Effects of supplemental chromium on production of cytokines by mitogen-stimulated bovine peripheral blood mononuclear cells [J].
Burton, JL ;
Nonnecke, BJ ;
Dubeski, PL ;
Elsasser, TH ;
Mallard, BA .
JOURNAL OF DAIRY SCIENCE, 1996, 79 (12) :2237-2246
[8]  
CAI TQ, 1994, AM J VET RES, V55, P934
[9]   SELENIUM DEFICIENCY ALTERS THE LIPOXYGENASE PATHWAY AND MITOGENIC RESPONSE IN BOVINE LYMPHOCYTES [J].
CAO, YZ ;
MADDOX, JF ;
MASTRO, AM ;
SCHOLZ, RW ;
HILDENBRANDT, G ;
REDDY, CC .
JOURNAL OF NUTRITION, 1992, 122 (11) :2121-2127
[10]  
Cebra CK, 2003, J VET INTERN MED, V17, P902, DOI 10.1892/0891-6640(2003)017&lt