Genes associated with the meningococcal capsule complex are also found in Neisseria gonorrhoeae

被引：22

作者：

Petering, H

Hammerschmidt, S

Frosch, M

vanPutten, JPM

Ison, CA

Robertson, BD

机构：

[1] ST MARYS HOSP,IMPERIAL COLL,SCH MED,DEPT MED MICROBIOL,LONDON W2 1PG,ENGLAND

[2] HANNOVER MED SCH,INST MED MIKROBIOL,D-30623 HANNOVER,GERMANY

[3] MAX PLANCK INST BIOL,D-72076 TUBINGEN,GERMANY

来源：

JOURNAL OF BACTERIOLOGY | 1996年 / 178卷 / 11期

基金：

英国惠康基金;

关键词：

D O I：

10.1128/jb.178.11.3342-3345.1996

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

A homolog of the meningococcal cps locus region E has been identified in Neisseria gonorrhoeae immediately upstream of the gonococcal region D locus. Region E has no detectable function in capsule biosynthesis in Neisseria meningitidis or in lipopolysaccharide biosynthesis in either organism. The open reading frame is homologous to proteins of unknown function in Escherichia coli and Haemophilus influenzae. Further analysis of the N. meningitidis cpa cluster has identified a second copy of region D encoding three additional open reading frames, including homologs of DNA methyltransferases. The organization of the region D and E genes in N. gonorrhoeae and N. meningitidis in relation to the cps genes provides some insight into the evolutionary origin of encapsulation in N. meningitidis.

引用

收藏

页码：3342 / 3345

页数：4

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