The Collaborative Pediatric Critical Care Research Network Critical Pertussis Study: Collaborative research in pediatric critical care medicine

被引：27

作者：

Burr, Jeri S. ^{[1
]}

Jenkins, Tammara L. ^{[2
]}

Harrison, Rick ^{[3
]}

Meert, Kathleen ^{[4
]}

Anand, K. J. S. ^{[5
]}

Berger, John T. ^{[6
]}

Zimmerman, Jerry ^{[7
]}

Carcillo, Joseph ^{[8
]}

Dean, J. Michael

Newth, Christopher J. L. ^{[9
]}

Willson, Douglas F. ^{[10
]}

Sanders, Ronald C., Jr. ^{[11
]}

Pollack, Murray M. ^{[12
]}

Harvill, Eric ^{[13
]}

Nicholson, Carol E. ^{[2
]}

机构：

[1] Univ Utah, Salt Lake City, UT 84112 USA

[2] Eunice Kennedy Shriver Natl Inst Child Hlth & Hum, NIH, Dept Hlth & Human Serv, Bethesda, MD USA

[3] Univ Calif Los Angeles, Mattel Childrens Hosp, Los Angeles, CA USA

[4] Childrens Hosp Michigan, Detroit, MI 48201 USA

[5] Univ Tennessee, Hlth Sci Ctr, Memphis, TN USA

[6] Childrens Natl Med Ctr, Washington, DC 20010 USA

[7] Seattle Childrens Hosp, Seattle, WA USA

[8] Childrens Hosp Pittsburgh, Pittsburgh, PA 15213 USA

[9] Childrens Hosp Los Angeles, Los Angeles, CA 90027 USA

[10] Univ Virginia, Childrens Hosp, Charlottesville, VA USA

[11] Arkansas Childrens Hosp, Little Rock, AR 72202 USA

[12] Phoenix Childrens Hosp, Phoenix, AZ USA

[13] Penn State Univ, University Pk, PA 16802 USA

来源：

PEDIATRIC CRITICAL CARE MEDICINE | 2011年 / 12卷 / 04期

关键词：

pertussis; respiratory failure; study design; out-comes; multiple organ system failure; advanced life support; EXTRACORPOREAL MEMBRANE-OXYGENATION; BORDETELLA-PERTUSSIS; PULMONARY-HYPERTENSION; NOSOCOMIAL PERTUSSIS; ADVISORY-COMMITTEE; INFANT PERTUSSIS; INTENSIVE-CARE; UNITED-STATES; RECOMMENDATIONS; DEATHS;

D O I：

10.1097/PCC.0b013e3181fe4058

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

Objective: To provide an updated overview of critical pertussis to the pediatric critical care community and describe a study of critical pertussis recently undertaken. Setting: The six sites, seven hospitals of the Collaborative Pediatric Critical Care Research Network, and 17 outside sites at academic medical centers with pediatric intensive care units. Results: Despite high coverage for childhood vaccination, pertussis causes substantial morbidity and mortality in US children, especially among infants. In pediatric intensive care units, Bordetella pertussis is a community-acquired pathogen associated with critical illness and death. The incidence of medical and developmental sequelae in critical pertussis survivors remains unknown, and the appropriate strategies for treatment and support remain unclear. The Collaborative Pediatric Critical Care Research Network Critical Pertussis Study has begun to evaluate critical pertussis in a prospective cohort. Conclusion: Research is urgently needed to provide an evidence base that might optimize management for critical pertussis, a serious, disabling, and too often fatal illness for U. S. children and those in the developing world. (Pediatr Crit Care Med 2011; 12:387-392)

引用

页码：387 / 392

页数：6

共 58 条

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Anonymous, 2005, Morbidity and Mortality Weekly Report, V54, P717

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