The National NeuroAIDS Tissue Consortium: a new paradigm in brain banking with an emphasis on infectious disease

被引：142

作者：

Morgello, S

Gelman, BB

Kozlowski, PB

Vinters, HV

Masliah, E

Cornford, M

Cavert, W

Marra, C

Grant, I

Singer, EJ

机构：

[1] CUNY, Mt Sinai Med Ctr, Dept Pathol, New York, NY 10029 USA

[2] Univ Texas, Med Branch, Dept Pathol, Galveston, TX 77550 USA

[3] New York State Inst Basic Res Dev Disabil, Staten Isl, NY 10314 USA

[4] Univ Calif San Diego, Dept Pathol, San Diego, CA 92103 USA

[5] Harbor UCLA Med Ctr, Dept Pathol, Los Angeles, CA USA

[6] Univ Calif Los Angeles, Dept Pathol & Lab Med, Los Angeles, CA USA

[7] Univ Calif Los Angeles, Dept Neurol, Los Angeles, CA 90024 USA

[8] Univ Minnesota, Dept Microbiol, Minneapolis, MN 55455 USA

[9] Univ Washington, Dept Neurol, Seattle, WA 98195 USA

[10] Univ Washington, Dept Med, Seattle, WA 98195 USA

[11] Univ Calif San Diego, San Diego, CA 92103 USA

[12] San Diego Vet Affairs Healthcare Syst, San Diego, CA USA

[13] Univ Calif Los Angeles, Dept Neurol, Los Angeles, CA 90024 USA

来源：

NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY | 2001年 / 27卷 / 04期

关键词：

AIDS; brain bank; HIV;

D O I：

10.1046/j.0305-1846.2001.00334.x

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The National NeuroAIDS Tissue Consortium (NNTC) was. founded in 1998, in response to the scientific need for well-characterized central nervous system (CNS) and peripheral nervous system (PNS) tissues and fluids from HIV-infected individuals. In addition to performing the routine functions of non-transplant anatomic tissue banks, the Consortium offers a unique model for the integration of independent research entities in order to provide well-characterized tissues and fluids for the international research community. Herein, we describe the structure of the Consortium, pointing out the inherent strengths of linking together multiple independent sites for the purpose of banking HIV-Infected nervous system tissues. We describe the neuropathology protocol that was adopted and successfully implemented at the four participating banks of the Consortium.

引用

页码：326 / 335

页数：10

共 13 条

[1] Principles and practice of 'high risk' brain banking
Bell, JE
Ironside, JW
[J]. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY, 1997, 23 (04) : 281 - 288
[2] DeArmond SJ, 1989, STRUCTURE HUMAN BRAI
[3] NEURONAL LOSS IN THE FRONTAL-CORTEX IN HIV-INFECTION
EVERALL, IP
LUTHERT, PJ
LANTOS, PL
[J]. LANCET, 1991, 337 (8750) : 1119 - 1121
[4] THE DECEDENT AFFAIRS OFFICE - A UNIQUE CENTRALIZED SERVICE
HAQUE, AK
COWAN, WT
SMITH, JH
[J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1991, 266 (10): : 1397 - 1399
[5] Hasin DS, 1996, AM J PSYCHIAT, V153, P1195
[6] Neuropathology and general autopsy findings in AIDS during the last 15 years
Jellinger, KA
Setinek, U
Drlicek, M
Böhm, G
Steurer, A
Lintner, F
[J]. ACTA NEUROPATHOLOGICA, 2000, 100 (02) : 213 - 220
[7] Johnson MD, 1997, ARCH PATHOL LAB MED, V121, P64
[8] Changes in pathological findings at autopsy in AIDS cases for the last 15 years
Masliah, E
DeTeresa, RM
Mallory, ME
Hansen, LA
[J]. AIDS, 2000, 14 (01) : 69 - 74
[9] Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection
Palella, FJ
Delaney, KM
Moorman, AC
Loveless, MO
Fuhrer, J
Satten, GA
Aschman, DJ
Holmberg, SD
[J]. NEW ENGLAND JOURNAL OF MEDICINE, 1998, 338 (13) : 853 - 860
[10] TORGERSON LD, 1999, INTERCHANGE, V14

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